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ENZYME

ENZYME entry: EC 3.1.3.108

PURL: https://purl.expasy.org/enzyme/EC/3.1.3.108
Accepted Name
nocturnin
Alternative Name(s)
nocturnin (curled)
Reaction catalysed
  • NADPH + H2O = phosphate + NADH
  • NADP(+) + H2O = phosphate + NAD(+)
Comment(s)
  • The mammalian mitochondrial enzyme is a rhythmically expressed protein that regulates metabolism under the control of circadian clock.
  • It has a slight preference for NADPH over NADP(+).
  • The archaeal enzyme, identified in Methanocaldococcus jannaschii, is bifunctional acting as NAD kinase (EC 2.7.1.23) and NADP phosphatase with a slight preference for NADP(+) over NADPH.
Cross-references
Rhea expert-curated reactions3.1.3.108
ExplorEnz3.1.3.108
IUBMB Enzyme Nomenclature3.1.3.108
UniProtKB/Swiss-Prot
Q9UK39, NOCT_HUMANO35710, NOCT_MOUSEQ9ET55, NOCT_RAT
BRENDA3.1.3.108
MetaCyc3.1.3.108
KEGG Ligand Database for Enzyme Nomenclature3.1.3.108
EC2PDB3.1.3.108
MEDLINEFind literature relating to 3.1.3.108

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