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ENZYME entry: EC 3.1.3.108

Accepted Name
Nocturnin.
Alternative Name(s)
Nocturnin (curled).
Reaction catalysed
  • NADPH + H(2)O <=> NADH + phosphate
  • NADP(+) + H(2)O <=> NAD(+) + phosphate
Comment(s)
  • The mammalian mitochondrial enzyme is a rhythmically expressed protein that regulates metabolism under the control of circadian clock.
  • It has a slight preference for NADPH over NADP(+).
  • The archaeal enzyme, identified in Methanocaldococcus jannaschii, is bifunctional acting as NAD kinase (EC 2.7.1.23) and NADP phosphatase with a slight preference for NADP(+) over NADPH.
Cross-references
BRENDA3.1.3.108
EC2PDB3.1.3.108
ExplorEnz3.1.3.108
PRIAM enzyme-specific profiles3.1.3.108
KEGG Ligand Database for Enzyme Nomenclature3.1.3.108
IUBMB Enzyme Nomenclature3.1.3.108
IntEnz3.1.3.108
MEDLINEFind literature relating to 3.1.3.108
MetaCyc3.1.3.108
Rhea expert-curated reactions3.1.3.108
UniProtKB/Swiss-Prot
Q9UK39, NOCT_HUMAN;  O35710, NOCT_MOUSE;  Q9ET55, NOCT_RAT;  

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