ENZYME entry: EC 3.1.3.108
| Accepted Name |
|---|
| Nocturnin.
|
| Alternative Name(s) |
|---|
| Nocturnin (curled). |
| Reaction catalysed |
|---|
- NADPH + H(2)O <=> NADH + phosphate
- NADP(+) + H(2)O <=> NAD(+) + phosphate
|
| Comment(s) |
|---|
- The mammalian mitochondrial enzyme is a rhythmically expressed
protein that regulates metabolism under the control of circadian
clock.
- It has a slight preference for NADPH over NADP(+).
- The archaeal enzyme, identified in Methanocaldococcus jannaschii,
is bifunctional acting as NAD kinase (EC 2.7.1.23) and NADP
phosphatase with a slight preference for NADP(+) over NADPH.
|
| Cross-references |
|---|
| BRENDA | 3.1.3.108 |
| EC2PDB | 3.1.3.108 |
| ExplorEnz | 3.1.3.108 |
| PRIAM enzyme-specific profiles | 3.1.3.108 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.3.108 |
| IUBMB Enzyme Nomenclature | 3.1.3.108 |
| IntEnz | 3.1.3.108 |
| MEDLINE | Find literature relating to 3.1.3.108 |
| MetaCyc | 3.1.3.108 |
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