Expasy logo

ENZYME

ENZYME entry: EC 3.1.3.56

PURL: https://purl.expasy.org/enzyme/EC/3.1.3.56
Accepted Name
inositol-polyphosphate 5-phosphatase
Alternative Name(s)
5PTase
D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase
D-myo-inositol 1,4,5-triphosphate 5-phosphatase
D-myo-inositol 1,4,5-trisphosphate 5-phosphatase
inosine triphosphatase
inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase
inositol-1,4,5-trisphosphate 5-phosphatase
inositol 1,4,5-trisphosphate phosphatase
inositol phosphate 5-phosphomonoesterase
inositol polyphosphate-5-phosphatase
inositol trisphosphate phosphomonoesterase
Ins(1,4,5)P3 5-phosphatase
InsP3/Ins(1,3,4,5)P4 5-phosphatase
L-myo-inositol 1,4,5-trisphosphate-monoesterase
myo-inositol-1,4,5-trisphosphate 5-phosphatase
type I inositol-polyphosphate phosphatase
Reaction catalysed
  • 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate
  • 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate
Comment(s)
This enzyme is distinguished from the family of enzymes classified under EC 3.1.3.36 by its inability to dephosphorylate inositol lipids.
Cross-references
BRENDA3.1.3.56
EC2PDB3.1.3.56
ExplorEnz3.1.3.56
KEGG Ligand Database for Enzyme Nomenclature3.1.3.56
IUBMB Enzyme Nomenclature3.1.3.56
MEDLINEFind literature relating to 3.1.3.56
MetaCyc3.1.3.56
Rhea expert-curated reactions3.1.3.56
UniProtKB/Swiss-Prot
Q17848, I5P1_CAEELQ29467, I5P1_CANLFQ14642, I5P1_HUMAN
Q7TNC9, I5P1_MOUSED3ZZX1, I5P1_RATP32019, I5P2_HUMAN
Q8K337, I5P2_MOUSEQ9BT40, INP5K_HUMANQ8C5L6, INP5K_MOUSE
Q84MA2, IP5P1_ARATHQ9FUR2, IP5P2_ARATHO80560, IP5PC_ARATH
Q9SYK4, IP5PD_ARATHQ01968, OCRL_HUMANQ6NVF0, OCRL_MOUSE
D3ZGS3, OCRL_RATQ15735, PI5PA_HUMANP59644, PI5PA_MOUSE
Q9JMC1, PI5PA_RATQ92835, SHIP1_HUMANQ9ES52, SHIP1_MOUSE
P97573, SHIP1_RATQ6P4S2, SHIP1_XENLA

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-