ENZYME entry: EC 3.1.4.45
| Accepted Name |
|---|
| N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.
|
| Alternative Name(s) |
|---|
| alpha-N-acetylglucosaminyl phosphodiesterase. |
| lysosomal alpha-N-acetylglucosaminidase. |
| Reaction catalysed |
|---|
| H2O + N(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] <=> H(+) + N(4)-[6-phospho-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] + N-acetyl-D-glucosamine |
| Comment(s) |
|---|
| Acts on a variety of compounds in which N-acetyl-D-glucosamine is
alpha-linked to a phosphate group, including the biosynthetic in
intermediates of the high mannose oligosaccharide components of some
lysosomal enzymes and the product of EC 2.7.8.17.
|
| Cross-references |
|---|
| BRENDA | 3.1.4.45 |
| EC2PDB | 3.1.4.45 |
| ExplorEnz | 3.1.4.45 |
| PRIAM enzyme-specific profiles | 3.1.4.45 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.4.45 |
| IUBMB Enzyme Nomenclature | 3.1.4.45 |
| IntEnz | 3.1.4.45 |
| MEDLINE | Find literature relating to 3.1.4.45 |
| MetaCyc | 3.1.4.45 |
| Rhea expert-curated reactions | 3.1.4.45 |
| UniProtKB/Swiss-Prot |
|
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