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ENZYME entry: EC 3.1.8.2

Accepted Name
Diisopropyl-fluorophosphatase.
Alternative Name(s)
DFPase.
OPA anhydrase.
OPAA.
Organophosphorus acid anhydrolase.
Somanase.
Tabunase.
Reaction catalysed
Diisopropyl fluorophosphate + H(2)O <=> diisopropyl phosphate + fluoride
Cofactor(s)
Divalent cation.
Comment(s)
  • Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).
  • Inhibited by chelating agents.
  • Related to EC 3.1.8.1.
  • Formerly EC 3.8.2.1.
Cross-references
BRENDA3.1.8.2
EC2PDB3.1.8.2
ExplorEnz3.1.8.2
PRIAM enzyme-specific profiles3.1.8.2
KEGG Ligand Database for Enzyme Nomenclature3.1.8.2
IUBMB Enzyme Nomenclature3.1.8.2
IntEnz3.1.8.2
MEDLINEFind literature relating to 3.1.8.2
MetaCyc3.1.8.2
Rhea expert-curated reactions3.1.8.2
UniProtKB/Swiss-Prot
Q7SIG4, DFPA_LOLVU;  Q44238, PEPQ_ALTSX;  P77814, PEPQ_PSEHA;  

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