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ENZYME

ENZYME entry: EC 3.11.1.1

Accepted Name
phosphonoacetaldehyde hydrolase
Alternative Name(s)
2-phosphonoacetylaldehyde phosphonohydrolase
phosphonatase
phosphonoacetylaldehyde phosphonohydrolase
Reaction catalysed
H2O + phosphonoacetaldehyde <=> acetaldehyde + H(+) + phosphate
Comment(s)
  • This enzyme destabilizes the C-P bond, by forming an imine between one of its lysine residues and the carbonyl group of the substrate, thus allowing this, normally stable, bond to be broken.
  • The mechanism is similar to that used by EC 4.1.2.13 to break a C-C bond.
Cross-references
BRENDA3.11.1.1
EC2PDB3.11.1.1
ExplorEnz3.11.1.1
PRIAM enzyme-specific profiles3.11.1.1
KEGG Ligand Database for Enzyme Nomenclature3.11.1.1
IUBMB Enzyme Nomenclature3.11.1.1
IntEnz3.11.1.1
MEDLINEFind literature relating to 3.11.1.1
MetaCyc3.11.1.1
Rhea expert-curated reactions3.11.1.1
UniProtKB/Swiss-Prot
Q183T0, PHNXW_CLOD6A0KJM0, PHNX_AERHHB6ES82, PHNX_ALISL
A0RBE8, PHNX_BACAHQ81TE1, PHNX_BACANB7JFQ8, PHNX_BACC0
Q73BH9, PHNX_BACC1B7IN18, PHNX_BACC2B7HH80, PHNX_BACC4
B7HK47, PHNX_BACC7O31156, PHNX_BACCEA7GML9, PHNX_BACCN
B9IUR5, PHNX_BACCQQ81G82, PHNX_BACCRQ63E46, PHNX_BACCZ
Q5L9P9, PHNX_BACFNQ64PZ2, PHNX_BACFRQ6HLM1, PHNX_BACHK
A9VKQ2, PHNX_BACMKQ2L1W2, PHNX_BORA1Q7WL48, PHNX_BORBR
Q7W7R1, PHNX_BORPAQ7VWH8, PHNX_BORPEQ2SHM4, PHNX_HAHCH
A6TFW3, PHNX_KLEP7Q88YN8, PHNX_LACPLQ38V12, PHNX_LATSS
B1HPR7, PHNX_LYSSCB8DKP2, PHNX_NITV9A6LFV1, PHNX_PARD8
B2T4N1, PHNX_PARPJQ13YI8, PHNX_PARXLA6V8P9, PHNX_PSEA7
B7UVR5, PHNX_PSEA8Q02JF2, PHNX_PSEABQ9I433, PHNX_PSEAE
Q1I7T9, PHNX_PSEE4Q4K9L7, PHNX_PSEF5C3JYI3, PHNX_PSEFS
A5W696, PHNX_PSEP1Q3K9Y2, PHNX_PSEPFQ88KT1, PHNX_PSEPK
Q8RSQ3, PHNX_PSEPUB1JBM6, PHNX_PSEPWA1SY91, PHNX_PSYIN
B5EXH2, PHNX_SALA4Q57SD2, PHNX_SALCHB5FKT7, PHNX_SALDC
B5QTI0, PHNX_SALEPB5R6T3, PHNX_SALG2B4T9C7, PHNX_SALHS
B4SWS4, PHNX_SALNSQ5PFR1, PHNX_SALPAA9MWZ8, PHNX_SALPB
C0Q7V6, PHNX_SALPCB5BDA0, PHNX_SALPKB4TMB2, PHNX_SALSV
Q8Z8W5, PHNX_SALTIQ7ZAP3, PHNX_SALTYA0LMC1, PHNX_SYNFM
A7N333, PHNX_VIBC1A5F051, PHNX_VIBC3Q9KLY5, PHNX_VIBCH
C3LVM1, PHNX_VIBCMQ87JL6, PHNX_VIBPAQ8D3M6, PHNX_VIBVU
Q7MF46, PHNX_VIBVY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.11.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.11.-.-
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