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ENZYME entry: EC 3.2.1.123

Accepted Name
Endoglycosylceramidase.
Alternative Name(s)
Endo-glucosylceramidase.
Endoglycoceramidase.
Oligoglycosylglucosylceramide glycohydrolase.
Reaction catalysed
Oligoglycosylglucosyl-(1<->1)-ceramide + H(2)O <=> ceramide + oligoglycosylglucose
Comment(s)
  • An enzyme from Rhodococcus sp. which degrades various acidic and neutral glycosphingolipids to oligosaccharides and ceramides, by cleaving a glucosyl bond.
  • Does not act on monoglycosylceramides (cf. EC 3.2.1.62).
Cross-references
BRENDA3.2.1.123
EC2PDB3.2.1.123
ExplorEnz3.2.1.123
PRIAM enzyme-specific profiles3.2.1.123
KEGG Ligand Database for Enzyme Nomenclature3.2.1.123
IUBMB Enzyme Nomenclature3.2.1.123
IntEnz3.2.1.123
MEDLINEFind literature relating to 3.2.1.123
MetaCyc3.2.1.123
Rhea expert-curated reactions3.2.1.123
UniProtKB/Swiss-Prot
Q9GV16, EGCSE_CYANO;  Q6L6S1, EGCSE_HYDVU;  A0A3S5YBC7, EGCSE_RHOH1;  

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