A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.2.1.130
| Accepted Name |
|---|
| Glycoprotein endo-alpha-1,2-mannosidase.
|
| Alternative Name(s) |
|---|
| Endo-alpha-D-mannosidase. |
| Reaction catalysed |
|---|
| GlcMan(9)GlcNAc(2)-[protein] + H(2)O <=> Man(8)GlcNAc(2)-[protein] (isomer 8A(1,2,3)B(1,2)) + alpha-D-glucosyl-(1->3)-alpha-D-mannopyranose |
| Comment(s) |
|---|
| The enzyme catalyzes the hydrolysis of the terminal alpha-D-glucosyl-
(1->3)-D-mannosyl unit from the GlcMan(9)(GlcNAc)(2) oligosaccharide
component of N-glucosylated proteins during their processing in the
Golgi apparatus.
|
| Cross-references |
|---|
| BRENDA | 3.2.1.130 |
| EC2PDB | 3.2.1.130 |
| ExplorEnz | 3.2.1.130 |
| PRIAM enzyme-specific profiles | 3.2.1.130 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.2.1.130 |
| IUBMB Enzyme Nomenclature | 3.2.1.130 |
| IntEnz | 3.2.1.130 |
| MEDLINE | Find literature relating to 3.2.1.130 |
| MetaCyc | 3.2.1.130 |
| UniProtKB/Swiss-Prot |
|
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ENZYME /
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