ENZYME entry: EC 3.2.1.130
Accepted Name |
Glycoprotein endo-alpha-1,2-mannosidase.
|
Alternative Name(s) |
Endo-alpha-D-mannosidase. |
Reaction catalysed |
GlcMan(9)GlcNAc(2)-[protein] + H(2)O <=> Man(8)GlcNAc(2)-[protein] (isomer 8A(1,2,3)B(1,2)) + alpha-D-glucosyl-(1->3)-alpha-D-mannopyranose |
Comment(s) |
The enzyme catalyzes the hydrolysis of the terminal alpha-D-glucosyl-
(1->3)-D-mannosyl unit from the GlcMan(9)(GlcNAc)(2) oligosaccharide
component of N-glucosylated proteins during their processing in the
Golgi apparatus.
|
Cross-references |
BRENDA | 3.2.1.130 |
EC2PDB | 3.2.1.130 |
ExplorEnz | 3.2.1.130 |
PRIAM enzyme-specific profiles | 3.2.1.130 |
KEGG Ligand Database for Enzyme Nomenclature | 3.2.1.130 |
IUBMB Enzyme Nomenclature | 3.2.1.130 |
IntEnz | 3.2.1.130 |
MEDLINE | Find literature relating to 3.2.1.130 |
MetaCyc | 3.2.1.130 |
UniProtKB/Swiss-Prot |
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