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ENZYME

ENZYME entry: EC 3.2.1.14

Accepted Name
chitinase
Alternative Name(s)
1,4-beta-poly-N-acetylglucosaminidase
chitodextrinase
poly-beta-glucosaminidase
Reaction catalysed
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins
Comment(s)
  • The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act.
  • Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. cf. EC 3.2.1.202.
Cross-references
BRENDA3.2.1.14
EC2PDB3.2.1.14
ExplorEnz3.2.1.14
PRIAM enzyme-specific profiles3.2.1.14
KEGG Ligand Database for Enzyme Nomenclature3.2.1.14
IUBMB Enzyme Nomenclature3.2.1.14
IntEnz3.2.1.14
MEDLINEFind literature relating to 3.2.1.14
MetaCyc3.2.1.14
Rhea expert-curated reactions3.2.1.14
UniProtKB/Swiss-Prot
P11218, AGI_URTDIP84708, CAI_PHAVUQ9W5U2, CHI10_DROME
Q5NB11, CHI10_ORYSJO74199, CHI11_METANQ10S66, CHI11_ORYSJ
P25765, CHI12_ORYSJQ838S2, CHI18_ENTFAP32470, CHI1_APHAL
D4AT07, CHI1_ARTBCQ5AAH2, CHI1_CANALP46876, CHI1_CANAX
P86078, CHI1_CAPAAP86081, CHI1_CAPCHP29137, CHI1_CASSA
Q1E3R8, CHI1_COCIMC5P230, CHI1_COCP7P0CB51, CHI1_COCPS
P85343, CHI1_GINBIQ39799, CHI1_GOSHIP11955, CHI1_HORVU
O14456, CHI1_METANE9ERT9, CHI1_METRAQ42993, CHI1_ORYSJ
P21225, CHI1_PEAH2A0L4, CHI1_PINMGP29025, CHI1_RHINI
P29026, CHI1_RHIOLP52403, CHI1_SOLTUP29115, CHI1_STROI
P85337, CHI1_TAXBAQ41596, CHI1_THECCP08252, CHI1_TOBAC
B6A876, CHI1_YERETQ06014, CHI2_ARAHYD4AVJ0, CHI2_ARTBC
Q09023, CHI2_BRANAP40953, CHI2_CANALP86079, CHI2_CAPAA
P86082, CHI2_CAPCHQ1EAR5, CHI2_COCIMP54197, CHI2_COCP7
Q39785, CHI2_GOSHIP23951, CHI2_HORVUQ4U4T0, CHI2_METAN
E9F9R9, CHI2_METRAQ7DNA1, CHI2_ORYSJP21226, CHI2_PEA
H2A0L5, CHI2_PINMGP29027, CHI2_RHIOLP52404, CHI2_SOLTU
P29116, CHI2_STROIP85338, CHI2_TAXBAP24091, CHI2_TOBAC
Q06350, CHI2_YEASTB6A879, CHI2_YERETD4B4X4, CHI33_ARTBC
Q12713, CHI33_TRIHAQ8NJQ5, CHI37_TRIHAQ06015, CHI3_ARAHY
P40954, CHI3_CANALQ6QDR4, CHI3_METANE9ENC6, CHI3_METRA
P24626, CHI3_ORYSJP52405, CHI3_SOLTUP85355, CHI3_TAXBA
P29059, CHI3_TOBACP48827, CHI42_TRIHAA6N6J0, CHI46_TRIHA
Q06016, CHI4_ARAHYQ06209, CHI4_BRANAQ5AM60, CHI4_CANAL
Q5NTA4, CHI4_CRYJAC9WJD0, CHI4_METANE9F7R6, CHI4_METRA
O04138, CHI4_ORYSJP27054, CHI4_PHAVUP52406, CHI4_SOLTU
A0A8G1A3Q5, CHI52_PAEXYO24598, CHI58_ARATHO24658, CHI59_ARATH
Q9M2U5, CHI5_ARATHQ7Y1Z0, CHI5_ORYSJP36361, CHI5_PHAVU
O22842, CHI61_ARATHO22841, CHI62_ARATHQ6K8R2, CHI6_ORYSJ
P16579, CHI6_POPTRQ9SAY3, CHI7_ORYSIQ7Y1Z1, CHI7_ORYSJ
Q7XCK6, CHI8_ORYSJP16061, CHI8_POPTRQ688M5, CHI9_ORYSJ
Q873Y0, CHIA1_ASPFMQ4WEP7, CHIA1_ASPFUA2QUQ2, CHIA1_ASPNC
Q92223, CHIA1_EMENDG5EB30, CHIA1_EMENIP20533, CHIA1_NIACI
Q06012, CHIA_ARAHYP19172, CHIA_ARATHQ95M17, CHIA_BOVIN
P36908, CHIA_CICARP17541, CHIA_CUCSAP13656, CHIA_ECOLI
A5FB63, CHIA_FLAJ1Q9BZP6, CHIA_HUMANP29022, CHIA_MAIZE
Q91XA9, CHIA_MOUSEP29024, CHIA_PHAANP32823, CHIA_PSEO7
Q6RY07, CHIA_RATQ9FRV1, CHIA_SECCEP07254, CHIA_SERMA
Q40114, CHIA_SOLCIQ05539, CHIA_SOLLCP29060, CHIA_TOBAC
Q873X9, CHIB1_ASPFME9QRF2, CHIB1_ASPFUG5EAZ3, CHIB1_EMENI
Q06013, CHIB_ARAHYP19171, CHIB_ARATHQ92222, CHIB_EMEND
P29023, CHIB_MAIZEP21227, CHIB_PEAP29031, CHIB_POPTR
P11797, CHIB_SERMAQ05540, CHIB_SOLLCP29061, CHIB_TOBAC
P51613, CHIB_VITVIO81862, CHIC_ARATHP29032, CHIC_POPTR
Q9FRV0, CHIC_SECCEQ05538, CHIC_SOLLCP27050, CHID_NIACI
Q05537, CHID_SOLLCP36910, CHIE_BETVUC0HLT5, CHIGU_GLUUR
P42820, CHIP_BETVUP17513, CHIP_TOBACP17514, CHIQ_TOBAC
Q13231, CHIT1_HUMANQ9D7Q1, CHIT1_MOUSEQ9SLP4, CHIT1_TULSB
Q9W092, CHIT2_DROMEQ7M443, CHIT2_TULSBP51614, CHIT3_VITVI
A0A1B1J8Z2, CHIT5_LOTJAP86473, CHIT_ACTCCP86181, CHIT_AVESA
P29030, CHIT_BRUMAQ11174, CHIT_CAEELP85084, CHIT_CARPA
P80052, CHIT_DIOJAP36362, CHIT_MANSEP41684, CHIT_NPVAC
O10363, CHIT_NPVOPP93680, CHIT_PERAEP29021, CHIT_PETHY
P06215, CHIT_PHAVUQ8I4R4, CHIT_PLAF7G1UH28, CHIT_PUNGR
P14529, CHIT_SACENP05315, CHIT_SOLTUP36909, CHIT_STRLI
P11220, CHIT_STRPLP84754, CHIT_STRVLP86977, CHIT_STRVO
C0HJM6, CHIT_TRISXP29029, CHIT_YEASTQ2VST0, CHIT_ZIZMA
P36907, CHIX_PEAQ05638, CHIX_STROIO24603, CHI_ARATH
P86955, CHI_PINMAP81241, CHLY_CARPAP23472, CHLY_HEVBR
P23473, CHLY_PARTHA0A072VEP0, CHT5A_MEDTRA0A072UR65, CHT5B_MEDTR
Q8S1V1, CLP_ORYSJP15326, IAMY_COILAP86799, IPLAA_MORAL
P86800, IPLAB_MORALP09805, KTXA_KLULA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-