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ENZYME

ENZYME entry: EC 3.2.1.48

PURL: https://purl.expasy.org/enzyme/EC/3.2.1.48
Accepted Name
sucrose alpha-glucosidase
Alternative Name(s)
sucrase
sucrase-isomaltase
sucrose alpha-glucohydrolase
Reaction catalysed
  • sucrose + H2O = beta-D-fructose + alpha-D-glucose
  • D-maltose + H2O = alpha-D-glucose + D-glucose
Comment(s)
  • The enzyme, found in animals, consists of two glycosyl hydrolase 31 domains side by side.
  • The N-terminal domain degrades isomaltose (cf. EC 3.2.1.10), while the C-terminal side degrades sucrose.
  • The enzyme recognizes and hydrolyzes the alpha-D-glucoside side of the sucrose molecule (a different enzyme, EC 3.2.1.26, recognizes and hydrolyzes the fructofuranoside group on the opposite side of sucrose).
Cross-references
Rhea expert-curated reactions3.2.1.48
ExplorEnz3.2.1.48
IUBMB Enzyme Nomenclature3.2.1.48
UniProtKB/Swiss-Prot
P14410, SUIS_HUMANB5THE3, SUIS_MOUSEP56729, SUIS_PIG
P07768, SUIS_RABITP23739, SUIS_RATO62653, SUIS_SUNMU
BRENDA3.2.1.48
MetaCyc3.2.1.48
KEGG Ligand Database for Enzyme Nomenclature3.2.1.48
MEDLINEFind literature relating to 3.2.1.48

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-