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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.2.1.10

Accepted Name
Oligo-1,6-glucosidase.
Alternative Name(s)
Alpha-methylglucosidase.
Isomaltase.
Oligosaccharide alpha-1,6-glucosidase.
Sucrase-isomaltase.
Reaction catalysed
Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose
Comment(s)
  • This enzyme, like EC 3.2.1.33, can release an alpha-1->6-linked glucose, whereas the shortest chain that can be released by EC 3.2.1.41, EC 3.2.1.142 and EC 3.2.1.68 is maltose.
  • It also hydrolyzes isomaltulose (palatinose), isomaltotriose and panose, but has no action on glycogen or phosphorylase limit dextrin.
  • The enzyme from intestinal mucosa is a single polypeptide chain that also catalyzes the reaction of EC 3.2.1.48.
  • Differs from EC 3.2.1.33 in its preference for short-chain substrates and in its not requiring the 6-glucosylated residue to be at a branch point, i.e. linked at both C-1 and C-4.
Cross-references
PROSITEPDOC00120
BRENDA3.2.1.10
EC2PDB3.2.1.10
ExplorEnz3.2.1.10
PRIAM enzyme-specific profiles3.2.1.10
KEGG Ligand Database for Enzyme Nomenclature3.2.1.10
IUBMB Enzyme Nomenclature3.2.1.10
IntEnz3.2.1.10
MEDLINEFind literature relating to 3.2.1.10
MetaCyc3.2.1.10
UniProtKB/Swiss-Prot
Q08295, IMA2_YEAST;  P40884, IMA5_YEAST;  P0CW40, MALX2_YEAST;  
P53051, MALX3_YEAST;  P0CW41, MALX4_YEAST;  O06994, O16G1_BACSU;  
O34364, O16G2_BACSU;  O05242, O16G3_BACSU;  P21332, O16G_BACCE;  
Q45101, O16G_BACCO;  P29093, O16G_BACF5;  Q9K8U9, O16G_BACHD;  
P29094, O16G_GEOTM;  P14410, SUIS_HUMAN;  P56729, SUIS_PIG;  
P07768, SUIS_RABIT;  P23739, SUIS_RAT;  O62653, SUIS_SUNMU;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-