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ENZYME entry: EC 3.3.2.14

Accepted Name
2,4-dinitroanisole O-demethylase.
Alternative Name(s)
2,4-dinitroanisole ether hydrolase.
DNAN demethylase.
Reaction catalysed
2,4-dinitroanisole + H(2)O <=> methanol + 2,4-dinitrophenol
Comment(s)
  • The enzyme, characterized from the bacterium Nocardioides sp. JS1661, is involved in the degradation of 2,4-dinitroanisole.
  • Unlike other known O-demethylases, such as EC 1.14.99.15 or EC 1.14.11.32, it does not require oxygen or electron donors, and produces methanol rather than formaldehyde.
Cross-references
BRENDA3.3.2.14
EC2PDB3.3.2.14
ExplorEnz3.3.2.14
PRIAM enzyme-specific profiles3.3.2.14
KEGG Ligand Database for Enzyme Nomenclature3.3.2.14
IUBMB Enzyme Nomenclature3.3.2.14
IntEnz3.3.2.14
MEDLINEFind literature relating to 3.3.2.14
MetaCyc3.3.2.14
Rhea expert-curated reactions3.3.2.14
UniProtKB/Swiss-Prot
A0A096ZEC9, DNHA_NOCS1;  A0A096ZED0, DNHB_NOCS1;  

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