Expasy logo

ENZYME

ENZYME entry: EC 3.4.11.26

PURL: https://purl.expasy.org/enzyme/EC/3.4.11.26
Accepted Name
intermediate cleaving peptidase 55
Reaction catalysed
The enzyme cleaves the 36-Pro-Pro-37 bond of cysteine desulfurase (EC 2.8.1.7) removing three amino acid residues (Tyr-Ser-Pro) from the N-terminus after cleavage by mitochondrial processing peptidase
Comment(s)
  • Icp55 removes the destabilizing N-terminal amino acid residues that are left after cleavage by the mitochondrial processing peptidase, leading to the stabilization of the substrate.
  • The enzyme can remove single amino acids or a short peptide, as in the case of cysteine desulfurase (EC 2.8.1.7), where three amino acids are removed.
Cross-references
Rhea expert-curated reactions3.4.11.26
ExplorEnz3.4.11.26
IUBMB Enzyme Nomenclature3.4.11.26
UniProtKB/Swiss-Prot
Q10439, ICP55_SCHPOP40051, ICP55_YEAST
BRENDA3.4.11.26
MetaCyc3.4.11.26
KEGG Ligand Database for Enzyme Nomenclature3.4.11.26
EC2PDB3.4.11.26
MEDLINEFind literature relating to 3.4.11.26

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-