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ENZYME entry: EC 3.4.13.23

Accepted Name
Cysteinylglycine-S-conjugate dipeptidase.
Reaction catalysed
An (L-cysteinylglycine)-S-conjugate + H(2)O <=> an L-cysteine-S-conjugate + glycine
Comment(s)
  • The enzyme participates in a widespread glutathione-mediated detoxification pathway.
  • In animals the activity is usually catalyzed by enzymes that have numerous additional activities, such as EC 3.4.11.1, EC 3.4.11.2 and EC 3.4.13.19.
  • However, in the bacterium Corynebacterium sp.Ax20, which degrades axillary secretions, the enzyme appears to be specific for this task.
Cross-references
BRENDA3.4.13.23
EC2PDB3.4.13.23
ExplorEnz3.4.13.23
PRIAM enzyme-specific profiles3.4.13.23
KEGG Ligand Database for Enzyme Nomenclature3.4.13.23
IUBMB Enzyme Nomenclature3.4.13.23
IntEnz3.4.13.23
MEDLINEFind literature relating to 3.4.13.23
MetaCyc3.4.13.23

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
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