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ENZYME

ENZYME entry: EC 3.4.14.5

PURL: https://purl.expasy.org/enzyme/EC/3.4.14.5
Accepted Name
dipeptidyl-peptidase IV
Alternative Name(s)
dipeptidyl aminopeptidase IV
DPP IV
Gly-Pro naphthylamidase
post-proline dipeptidyl aminopeptidase IV
Xaa-Pro-dipeptidylaminopeptidase
Reaction catalysed
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline
Comment(s)
  • A membrane-bound serine-type peptidase in mammals.
  • EC 3.4.14.11 catalyzes a similar reaction.
  • Belongs to peptidase family S9B.
Cross-references
BRENDA3.4.14.5
EC2PDB3.4.14.5
ExplorEnz3.4.14.5
KEGG Ligand Database for Enzyme Nomenclature3.4.14.5
IUBMB Enzyme Nomenclature3.4.14.5
MEDLINEFind literature relating to 3.4.14.5
MetaCyc3.4.14.5
Rhea expert-curated reactions3.4.14.5
UniProtKB/Swiss-Prot
Q6F3I7, DAP4_PSEMXF0U7H7, DAPB_AJEC8C0NUQ8, DAPB_AJECG
C6HRC7, DAPB_AJECHA6RBI0, DAPB_AJECNC5GVF3, DAPB_AJEDR
D4AQT0, DAPB_ARTBCE4UYL6, DAPB_ARTGPC5FYZ3, DAPB_ARTOC
A1CJQ1, DAPB_ASPCLB0XYK8, DAPB_ASPFCB8N076, DAPB_ASPFN
Q4WX13, DAPB_ASPFUA2QEK7, DAPB_ASPNCQ96VT7, DAPB_ASPNG
Q2UPW4, DAPB_ASPORQ0CXB1, DAPB_ASPTNC5JC30, DAPB_BLAGS
A6SL49, DAPB_BOTFBQ2HF90, DAPB_CHAGBC5P334, DAPB_COCP7
E9CUF4, DAPB_COCPSE3QKD2, DAPB_COLGMQ5B934, DAPB_EMENI
C7YYG9, DAPB_FUSV7F0XS04, DAPB_GROCLE9ED72, DAPB_METAQ
E9ETL5, DAPB_METRAA1D7R6, DAPB_NEOFIQ7SHU8, DAPB_NEUCR
C1GT79, DAPB_PARBAC1FZL3, DAPB_PARBDC0S7H1, DAPB_PARBP
B6HFS8, DAPB_PENRWQ0UVK7, DAPB_PHANOB2A951, DAPB_PODAN
A4QYQ5, DAPB_PYRO7B2WC36, DAPB_PYRTRE3S9K3, DAPB_PYRTT
A7EQZ1, DAPB_SCLS1D1Z9B4, DAPB_SORMKB6QVW4, DAPB_TALMQ
B8MTH6, DAPB_TALSND4DCG0, DAPB_TRIVHD5GM60, DAPB_TUBMM
C4JHY5, DAPB_UNCREC9SJ15, DAPB_VERA1D4APE2, DPP4_ARTBC
C5FJE3, DPP4_ARTOCA0S5V9, DPP4_ARTOTA1CHP1, DPP4_ASPCL
B0Y6C5, DPP4_ASPFCB8N970, DPP4_ASPFNQ4WPH9, DPP4_ASPFU
Q2UH35, DPP4_ASPORP81425, DPP4_BOVINQ5AZ42, DPP4_EMENI
Q9N2I7, DPP4_FELCAP27487, DPP4_HUMANP28843, DPP4_MOUSE
A1CX29, DPP4_NEOFIP22411, DPP4_PIGP14740, DPP4_RAT
A7UKV8, DPP4_TRIEQQ5J6J3, DPP4_TRIRUB6V868, DPP4_TRITO
D4CZ59, DPP4_TRIVHQ6V1X1, DPP8_HUMANQ80YA7, DPP8_MOUSE
A0A2R8QP51, DPP9_DANREQ86TI2, DPP9_HUMANQ8BVG4, DPP9_MOUSE
A5D7B7, SEPR_BOVINQ12884, SEPR_HUMANP97321, SEPR_MOUSE
P0DRB8, VDDP4_VESVEB1A4F7, VDDP4_VESVUB2D0J4, VDPP4_APIME

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-