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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Peptidyl-dipeptidase B.
Alternative Name(s)
Atrial di-(tri-)peptidyl carboxylase.
Atriopeptin convertase.
Dipeptidyl carboxyhydrolase.
Reaction catalysed
Release of a C-terminal dipeptide or exceptionally a tripeptide
  • A membrane-bound, zinc metallopeptidase located in mammalian atrial, but not ventricular, myocytes.
  • Although it is capable of converting the 126-residue atriopeptin III directly to atriopeptin I by releasing a C-terminal tripeptide Phe- Arg-Tyr, it is generally restricted to the release of dipeptides.
  • In contrast to EC it displays no chlorine dependence and shows no action on angiotensin I.
  • Conversely, peptidyl-dipeptidase a is unable to release Phe-Arg from the C-terminus of atriopeptin II.
PRIAM enzyme-specific profiles3.4.15.4
KEGG Ligand Database for Enzyme Nomenclature3.4.15.4
IUBMB Enzyme Nomenclature3.4.15.4
MEDLINEFind literature relating to

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.15.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-