Expasy logo

ENZYME

ENZYME entry: EC 3.4.17.13

PURL: https://purl.expasy.org/enzyme/EC/3.4.17.13
Accepted Name
muramoyltetrapeptide carboxypeptidase
Alternative Name(s)
carboxypeptidase IIW
Reaction catalysed
N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioate + D-alanine
Comment(s)
  • Variants are known from various microorganisms.
  • Involved in peptidoglycan synthesis, catalyzing both decarboxylation and transpeptidation.
  • Stimulated by divalent cations such as magnesium and calcium, but not zinc.
  • Inhibited by thiol-blocking reagents, but unaffected by penicillin.
Cross-references
BRENDA3.4.17.13
EC2PDB3.4.17.13
ExplorEnz3.4.17.13
KEGG Ligand Database for Enzyme Nomenclature3.4.17.13
IUBMB Enzyme Nomenclature3.4.17.13
MEDLINEFind literature relating to 3.4.17.13
MetaCyc3.4.17.13
Rhea expert-curated reactions3.4.17.13
UniProtKB/Swiss-Prot
Q8XDJ8, LDCA_ECO57P59238, LDCA_ECOL6P76008, LDCA_ECOLI
Q9HTZ1, LDC_PSEAEP0AFV6, MEPS_ECO57P0AFV5, MEPS_ECOL6
P0AFV4, MEPS_ECOLIP0AFV7, MEPS_SHIFLQ9VYX7, PGPSA_DROME

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.17.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-