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ENZYME

ENZYME entry: EC 3.4.19.14

Accepted Name
leukotriene-C4 hydrolase
Alternative Name(s)
gamma-glutamyl leukotrienase
Reaction catalysed
H2O + leukotriene C4 <=> L-glutamate + leukotriene D4
Comment(s)
The mouse enzyme is specific for leukotriene C4, while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC 3.4.19.13).
Cross-references
BRENDA3.4.19.14
EC2PDB3.4.19.14
ExplorEnz3.4.19.14
PRIAM enzyme-specific profiles3.4.19.14
KEGG Ligand Database for Enzyme Nomenclature3.4.19.14
IUBMB Enzyme Nomenclature3.4.19.14
IntEnz3.4.19.14
MEDLINEFind literature relating to 3.4.19.14
MetaCyc3.4.19.14
Rhea expert-curated reactions3.4.19.14
UniProtKB/Swiss-Prot
D4B387, GGT1_ARTBCP19440, GGT1_HUMANQ60928, GGT1_MOUSE
P20735, GGT1_PIGP07314, GGT1_RATP36269, GGT5_HUMAN
Q9Z2A9, GGT5_MOUSEQ9QWE9, GGT5_RAT

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