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ENZYME entry: EC 3.4.21.21

Accepted Name
coagulation factor VIIa.
Reaction catalysed
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa
Comment(s)
  • Formed from the precursor factor VII.
  • The cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human.
  • Belongs to peptidase family S1.
Cross-references
BRENDA3.4.21.21
EC2PDB3.4.21.21
ExplorEnz3.4.21.21
PRIAM enzyme-specific profiles3.4.21.21
KEGG Ligand Database for Enzyme Nomenclature3.4.21.21
IUBMB Enzyme Nomenclature3.4.21.21
IntEnz3.4.21.21
MEDLINEFind literature relating to 3.4.21.21
MetaCyc3.4.21.21
Rhea expert-curated reactions3.4.21.21
UniProtKB/Swiss-Prot
P22457, FA7_BOVIN;  P08709, FA7_HUMAN;  P70375, FA7_MOUSE;  
Q2F9P4, FA7_PANPA;  Q2F9P2, FA7_PANTR;  P98139, FA7_RABIT;  
Q8K3U6, FA7_RAT;  

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