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ENZYME

ENZYME class: 3.4.21.-

PURL: https://purl.expasy.org/enzyme/EC/3.4.21.-

Release of 18-Jun-25

3.-.-.-: Hydrolases
3.4.-.-: Acting on peptide bonds (peptidases)
3.4.21.-: Serine endopeptidases

All UniProtKB/Swiss-Prot entries corresponding to class 3.4.21.-.

The following ENZYME entries belong to class 3.4.21.-:

3.4.21.1chymotrypsin
3.4.21.2chymotrypsin C
3.4.21.3metridin
3.4.21.4trypsin
3.4.21.5thrombin
3.4.21.6coagulation factor Xa
3.4.21.7plasmin
3.4.21.8Transferred entry: 3.4.21.34 and 3.4.21.35
3.4.21.9enteropeptidase
3.4.21.10acrosin
3.4.21.11Transferred entry: 3.4.21.36 and 3.4.21.37
3.4.21.12alpha-lytic endopeptidase
3.4.21.13Transferred entry: 3.4.16.5 and 3.4.16.6
3.4.21.14Transferred entry: 3.4.21.62, 3.4.21.63, 3.4.21.64, 3.4.21.65 and
3.4.21.143.4.21.67
3.4.21.15Transferred entry: 3.4.21.63
3.4.21.16Deleted entry
3.4.21.17Deleted entry
3.4.21.18Deleted entry
3.4.21.19glutamyl endopeptidase
3.4.21.20cathepsin G
3.4.21.21coagulation factor VIIa
3.4.21.22coagulation factor IXa
3.4.21.23Deleted entry
3.4.21.24Deleted entry
3.4.21.25cucumisin
3.4.21.26prolyl oligopeptidase
3.4.21.27coagulation factor XIa
3.4.21.28Transferred entry: 3.4.21.74
3.4.21.29Transferred entry: 3.4.21.74
3.4.21.30Transferred entry: 3.4.21.74
3.4.21.31Transferred entry: 3.4.21.68 and 3.4.21.73
3.4.21.32brachyurin
3.4.21.33Deleted entry
3.4.21.34plasma kallikrein
3.4.21.35tissue kallikrein
3.4.21.36pancreatic elastase
3.4.21.37leukocyte elastase
3.4.21.38coagulation factor XIIa
3.4.21.39chymase
3.4.21.40Deleted entry
3.4.21.41complement subcomponent C1r
3.4.21.42complement subcomponent C1s
3.4.21.43classical-complement-pathway C3/C5 convertase
3.4.21.44Transferred entry: 3.4.21.43
3.4.21.45complement factor I
3.4.21.46complement factor D
3.4.21.47alternative-complement-pathway C3/C5 convertase
3.4.21.48cerevisin
3.4.21.49hypodermin C
3.4.21.50lysyl endopeptidase
3.4.21.51Deleted entry
3.4.21.52Deleted entry
3.4.21.53endopeptidase La
3.4.21.54gamma-renin
3.4.21.55venombin AB
3.4.21.56Deleted entry
3.4.21.57leucyl endopeptidase
3.4.21.58Deleted entry
3.4.21.59tryptase
3.4.21.60scutelarin
3.4.21.61kexin
3.4.21.62subtilisin
3.4.21.63oryzin
3.4.21.64peptidase K
3.4.21.65thermomycolin
3.4.21.66thermitase
3.4.21.67endopeptidase So
3.4.21.68t-plasminogen activator
3.4.21.69activated protein C (thrombin-activated peptidase)
3.4.21.70pancreatic endopeptidase E
3.4.21.71pancreatic elastase II
3.4.21.72IgA-specific serine endopeptidase
3.4.21.73u-plasminogen activator
3.4.21.74venombin A
3.4.21.75furin
3.4.21.76myeloblastin
3.4.21.77semenogelase
3.4.21.78granzyme A
3.4.21.79granzyme B
3.4.21.80streptogrisin A
3.4.21.81streptogrisin B
3.4.21.82glutamyl endopeptidase II
3.4.21.83oligopeptidase B
3.4.21.84limulus clotting factor C
3.4.21.85limulus clotting factor B
3.4.21.86limulus clotting enzyme
3.4.21.87Transferred entry: 3.4.23.49
3.4.21.88repressor LexA
3.4.21.89signal peptidase I
3.4.21.90togavirin
3.4.21.91flavivirin
3.4.21.92endopeptidase Clp
3.4.21.93proprotein convertase 1
3.4.21.94proprotein convertase 2
3.4.21.95snake venom factor V activator
3.4.21.96lactocepin
3.4.21.97assemblin
3.4.21.98hepacivirin
3.4.21.99spermosin
3.4.21.100sedolisin
3.4.21.101xanthomonalisin
3.4.21.102C-terminal processing peptidase
3.4.21.103physarolisin
3.4.21.104mannan-binding lectin-associated serine protease-2
3.4.21.105rhomboid protease
3.4.21.106hepsin
3.4.21.107peptidase Do
3.4.21.108HtrA2 peptidase
3.4.21.109matriptase
3.4.21.110C5a peptidase
3.4.21.111aqualysin 1
3.4.21.112site-1 protease
3.4.21.113pestivirus NS3 polyprotein peptidase
3.4.21.114equine arterivirus serine peptidase
3.4.21.115infectious pancreatic necrosis birnavirus Vp4 peptidase
3.4.21.116SpoIVB peptidase
3.4.21.117stratum corneum chymotryptic enzyme
3.4.21.118kallikrein 8
3.4.21.119kallikrein 13
3.4.21.120oviductin
3.4.21.121Lys-Lys/Arg-Xaa endopeptidase
3.4.21.122transmembrane protease serine 2
3.4.21.123kumamolysin