Home  |  Contact
Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am CEST. Apologies for the inconvenience.

ENZYME entry: EC

Accepted Name
coagulation factor XIIa.
Alternative Name(s)
Hageman factor.
Reaction catalysed
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa
  • Also activates plasma prekallikrein and plasminogen.
  • Formed from the proenzyme, factor XII, by plasma kallikrein or factor XIIa.
  • Belongs to peptidase family S1.
PRIAM enzyme-specific profiles3.4.21.38
KEGG Ligand Database for Enzyme Nomenclature3.4.21.38
IUBMB Enzyme Nomenclature3.4.21.38
MEDLINEFind literature relating to
Rhea expert-curated reactions3.4.21.38
P98140, FA12_BOVIN;  Q04962, FA12_CAVPO;  P00748, FA12_HUMAN;  
Q80YC5, FA12_MOUSE;  O97507, FA12_PIG;  D3ZTE0, FA12_RAT;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-