A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.21.43
| Accepted Name |
|---|
| Classical-complement-pathway C3/C5 convertase.
|
| Alternative Name(s) |
|---|
| C3 convertase. |
| C5 convertase. |
| Complement C2. |
| Reaction catalysed |
|---|
| Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b |
| Comment(s) |
|---|
- A complex of complement fragments C4b, C2a and C2b.
- Belongs to peptidase family S1.
- Formerly EC 3.4.21.44.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.43 |
| EC2PDB | 3.4.21.43 |
| ExplorEnz | 3.4.21.43 |
| PRIAM enzyme-specific profiles | 3.4.21.43 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.43 |
| IUBMB Enzyme Nomenclature | 3.4.21.43 |
| IntEnz | 3.4.21.43 |
| MEDLINE | Find literature relating to 3.4.21.43 |
| MetaCyc | 3.4.21.43 |
| UniProtKB/Swiss-Prot |
|
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