Expasy logo

ENZYME

ENZYME entry: EC 3.4.21.43

Accepted Name
classical-complement-pathway C3/C5 convertase
Alternative Name(s)
C3 convertase
C5 convertase
complement C2
Reaction catalysed
Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b
Comment(s)
  • A complex of complement fragments C4b, C2a and C2b.
  • Belongs to peptidase family S1.
  • Formerly EC 3.4.21.44.
Cross-references
BRENDA3.4.21.43
EC2PDB3.4.21.43
ExplorEnz3.4.21.43
PRIAM enzyme-specific profiles3.4.21.43
KEGG Ligand Database for Enzyme Nomenclature3.4.21.43
IUBMB Enzyme Nomenclature3.4.21.43
IntEnz3.4.21.43
MEDLINEFind literature relating to 3.4.21.43
MetaCyc3.4.21.43
Rhea expert-curated reactions3.4.21.43
UniProtKB/Swiss-Prot
Q3SYW2, CO2_BOVINQ863A0, CO2_GORGOP06681, CO2_HUMAN
P21180, CO2_MOUSEQ8SQ74, CO2_PANTRQ8SQ75, CO2_PONPY

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-