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ENZYME entry: EC 3.4.21.43
Accepted Name |
classical-complement-pathway C3/C5 convertase.
|
Alternative Name(s) |
C3 convertase. |
C5 convertase. |
complement C2. |
Reaction catalysed |
Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b |
Comment(s) |
- A complex of complement fragments C4b, C2a and C2b.
- Belongs to peptidase family S1.
- Formerly EC 3.4.21.44.
|
Cross-references |
BRENDA | 3.4.21.43 |
EC2PDB | 3.4.21.43 |
ExplorEnz | 3.4.21.43 |
PRIAM enzyme-specific profiles | 3.4.21.43 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.43 |
IUBMB Enzyme Nomenclature | 3.4.21.43 |
IntEnz | 3.4.21.43 |
MEDLINE | Find literature relating to 3.4.21.43 |
MetaCyc | 3.4.21.43 |
Rhea expert-curated reactions | 3.4.21.43 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-