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ENZYME entry: EC 3.4.21.45
Accepted Name |
complement factor I.
|
Alternative Name(s) |
C3b/C4b inactivator. |
C3b inactivator. |
complement component C3b inactivator. |
Reaction catalysed |
Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage |
Comment(s) |
- Cleavage of complement subcomponent C3b requires its binding to
cofactor H or complement receptor CR1; cleavage of iC3b requires
complement receptor CR1; cleavage of C4b requires C4b-binding
protein.
- Belongs to peptidase family S1.
|
Cross-references |
BRENDA | 3.4.21.45 |
EC2PDB | 3.4.21.45 |
ExplorEnz | 3.4.21.45 |
PRIAM enzyme-specific profiles | 3.4.21.45 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.45 |
IUBMB Enzyme Nomenclature | 3.4.21.45 |
IntEnz | 3.4.21.45 |
MEDLINE | Find literature relating to 3.4.21.45 |
MetaCyc | 3.4.21.45 |
Rhea expert-curated reactions | 3.4.21.45 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
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