ENZYME entry: EC 3.4.21.46
Accepted Name |
Complement factor D.
|
Alternative Name(s) |
C3 convertase activator. |
C3 proactivator convertase. |
Reaction catalysed |
Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor |
Comment(s) |
- A component of the alternative pathway of complement activation.
- This reaction is analogous to the activation of complement component
C2 by activated complement subcomponent C1s.
- Belongs to peptidase family S1.
|
Cross-references |
PROSITE | PDOC00124 |
BRENDA | 3.4.21.46 |
EC2PDB | 3.4.21.46 |
ExplorEnz | 3.4.21.46 |
PRIAM enzyme-specific profiles | 3.4.21.46 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.46 |
IUBMB Enzyme Nomenclature | 3.4.21.46 |
IntEnz | 3.4.21.46 |
MEDLINE | Find literature relating to 3.4.21.46 |
MetaCyc | 3.4.21.46 |
UniProtKB/Swiss-Prot |
|
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