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ENZYME entry: EC 3.4.21.54

Accepted Name
Gamma-renin.
Reaction catalysed
Cleavage of the Leu-|-Leu bond in synthetic tetradecapeptide renin substrate, to produce angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes Bz-Arg-p-nitroanilide
Comment(s)
  • Unlike EC 3.4.23.15, does not act on natural angiotensinogen.
  • A member of the tissue kallikrein family, from submandibular glands of male mice.
  • Belongs to peptidase family S1.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.54
EC2PDB3.4.21.54
ExplorEnz3.4.21.54
PRIAM enzyme-specific profiles3.4.21.54
KEGG Ligand Database for Enzyme Nomenclature3.4.21.54
IUBMB Enzyme Nomenclature3.4.21.54
IntEnz3.4.21.54
MEDLINEFind literature relating to 3.4.21.54
MetaCyc3.4.21.54
UniProtKB/Swiss-Prot
P04071, K1B16_MOUSE

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