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ENZYME entry: EC 3.4.21.59
| Accepted Name |
|---|
| tryptase.
|
| Alternative Name(s) |
|---|
| lung tryptase. |
| mast cell protease II. |
| mast cell tryptase. |
| pituitary tryptase. |
| skin tryptase. |
| Reaction catalysed |
|---|
| Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa, but with more restricted specificity than trypsin |
| Comment(s) |
|---|
- Occurs as a tetrameric molecule with high affinity for heparin,
in mast cell granules.
- Not inhibited by alpha-1-proteinase inhibitor of alpha-2-
macroglobulin.
- Belongs to peptidase family S1.
|
| Cross-references |
|---|
| BRENDA | 3.4.21.59 |
| EC2PDB | 3.4.21.59 |
| ExplorEnz | 3.4.21.59 |
| PRIAM enzyme-specific profiles | 3.4.21.59 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.59 |
| IUBMB Enzyme Nomenclature | 3.4.21.59 |
| IntEnz | 3.4.21.59 |
| MEDLINE | Find literature relating to 3.4.21.59 |
| MetaCyc | 3.4.21.59 |
| Rhea expert-curated reactions | 3.4.21.59 |
| UniProtKB/Swiss-Prot |
| Q15661, TRYB1_HUMAN; | Q02844, TRYB1_MOUSE; | P27435, TRYB1_RAT; |
| P20231, TRYB2_HUMAN; | P21845, TRYB2_MOUSE; | P50343, TRYB2_RAT; |
| Q9BZJ3, TRYD_HUMAN; | P15944, TRYT_CANLF; | P50342, TRYT_MERUN; |
| Q9N2D1, TRYT_PIG; | Q9XSM2, TRYT_SHEEP; |
|
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-