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ENZYME entry: EC 3.4.21.7

Accepted Name
Plasmin.
Alternative Name(s)
Fibrinase.
Fibrinolysin.
Reaction catalysed
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products
Comment(s)
  • Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin.
  • Belongs to peptidase family S1.
  • Formerly EC 3.4.4.14.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.7
EC2PDB3.4.21.7
ExplorEnz3.4.21.7
PRIAM enzyme-specific profiles3.4.21.7
KEGG Ligand Database for Enzyme Nomenclature3.4.21.7
IUBMB Enzyme Nomenclature3.4.21.7
IntEnz3.4.21.7
MEDLINEFind literature relating to 3.4.21.7
MetaCyc3.4.21.7
Rhea expert-curated reactions3.4.21.7
UniProtKB/Swiss-Prot
P06868, PLMN_BOVIN;  P80009, PLMN_CANLF;  Q7M323, PLMN_CAPHI;  
Q29485, PLMN_ERIEU;  P80010, PLMN_HORSE;  P00747, PLMN_HUMAN;  
O18783, PLMN_MACEU;  P12545, PLMN_MACMU;  P20918, PLMN_MOUSE;  
P33574, PLMN_PETMA;  P06867, PLMN_PIG;  Q5R8X6, PLMN_PONAB;  
Q01177, PLMN_RAT;  P81286, PLMN_SHEEP;  P83169, PLMN_STRCA;  

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