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ENZYME entry: EC 3.4.21.71

Accepted Name
Pancreatic elastase II.
Reaction catalysed
Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes elastin
Comment(s)
  • Formed by activation of proelastase II from mammalian pancreas by trypsin.
  • Usually, only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species; human pancreatic elastase is of type II.
  • Belongs to peptidase family S1.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.71
EC2PDB3.4.21.71
ExplorEnz3.4.21.71
PRIAM enzyme-specific profiles3.4.21.71
KEGG Ligand Database for Enzyme Nomenclature3.4.21.71
IUBMB Enzyme Nomenclature3.4.21.71
IntEnz3.4.21.71
MEDLINEFind literature relating to 3.4.21.71
MetaCyc3.4.21.71
Rhea expert-curated reactions3.4.21.71
UniProtKB/Swiss-Prot
Q29461, CEL2A_BOVIN;  P08217, CEL2A_HUMAN;  P05208, CEL2A_MOUSE;  
P08419, CEL2A_PIG;  P00774, CEL2A_RAT;  P08218, CEL2B_HUMAN;  

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