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ENZYME entry: EC 3.4.23.41
Accepted Name |
yapsin 1.
|
Alternative Name(s) |
aspartic proteinase 3. |
yeast aspartic protease 3. |
Reaction catalysed |
Hydrolyzes various precursor proteins with Arg or Lys in P1, and commonly Arg or Lys also in P2. The P3 amino acid is usually non-polar, but otherwise additional basic amino acids are favorable in both non-prime and prime positions |
Comment(s) |
- Weakly inhibited by pepstatin.
- Can partially substitute for kexin in a deficient strain of
Saccharomyces cerevisiae.
- The homologous product of the MKC7 gene (S.cerevisiae) has similar
catalytic activity and has been termed yapsin 2.
- Belongs to peptidase family A1.
|
Cross-references |
BRENDA | 3.4.23.41 |
EC2PDB | 3.4.23.41 |
ExplorEnz | 3.4.23.41 |
PRIAM enzyme-specific profiles | 3.4.23.41 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.41 |
IUBMB Enzyme Nomenclature | 3.4.23.41 |
IntEnz | 3.4.23.41 |
MEDLINE | Find literature relating to 3.4.23.41 |
MetaCyc | 3.4.23.41 |
Rhea expert-curated reactions | 3.4.23.41 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
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