ENZYME entry: EC 3.4.23.41
| Accepted Name |
|---|
| yapsin 1.
|
| Alternative Name(s) |
|---|
| aspartic proteinase 3. |
| yeast aspartic protease 3. |
| Reaction catalysed |
|---|
| Hydrolyzes various precursor proteins with Arg or Lys in P1, and commonly Arg or Lys also in P2. The P3 amino acid is usually non-polar, but otherwise additional basic amino acids are favorable in both non-prime and prime positions |
| Comment(s) |
|---|
- Weakly inhibited by pepstatin.
- Can partially substitute for kexin in a deficient strain of
Saccharomyces cerevisiae.
- The homologous product of the MKC7 gene (S.cerevisiae) has similar
catalytic activity and has been termed yapsin 2.
- Belongs to peptidase family A1.
|
| Cross-references |
|---|
| BRENDA | 3.4.23.41 |
| EC2PDB | 3.4.23.41 |
| ExplorEnz | 3.4.23.41 |
| PRIAM enzyme-specific profiles | 3.4.23.41 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.41 |
| IUBMB Enzyme Nomenclature | 3.4.23.41 |
| IntEnz | 3.4.23.41 |
| MEDLINE | Find literature relating to 3.4.23.41 |
| MetaCyc | 3.4.23.41 |
| Rhea expert-curated reactions | 3.4.23.41 |
| UniProtKB/Swiss-Prot |
|
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