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ENZYME

ENZYME entry: EC 3.4.24.13

PURL: https://purl.expasy.org/enzyme/EC/3.4.24.13
Accepted Name
IgA-specific metalloendopeptidase
Alternative Name(s)
IgA protease
immunoglobulin A1 proteinase
Reaction catalysed
Cleavage of Pro-|-Thr bond in the hinge region of the heavy chain of human IgA
Comment(s)
  • Found in several pathogenic species of Streptococcus such as S.sanguis and S.pneumoniae.
  • There is also an IgA-specific prolyl endopeptidase of serine-type (see EC 3.4.21.72).
  • Belongs to peptidase family M26.
Cross-references
BRENDA3.4.24.13
EC2PDB3.4.24.13
ExplorEnz3.4.24.13
KEGG Ligand Database for Enzyme Nomenclature3.4.24.13
IUBMB Enzyme Nomenclature3.4.24.13
MEDLINEFind literature relating to 3.4.24.13
MetaCyc3.4.24.13
Rhea expert-curated reactions3.4.24.13
UniProtKB/Swiss-Prot
Q97QP7, IGA1A_STRPNQ54875, IGA1B_STREEQ59947, IGA1_STRR6
Q59986, IGA1_STRSA

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