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ENZYME entry: EC 3.4.21.72
Accepted Name |
IgA-specific serine endopeptidase.
|
Alternative Name(s) |
IgA protease. |
immunoglobulin A1 protease. |
Reaction catalysed |
Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known |
Comment(s) |
- Species variants differing slightly in specificity are secreted by
Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus
influenzae.
- Some other bacterial endopeptidases with similar specificity are of
metallotype (see EC 3.4.24.13).
- Belongs to peptidase family S6.
|
Cross-references |
BRENDA | 3.4.21.72 |
EC2PDB | 3.4.21.72 |
ExplorEnz | 3.4.21.72 |
PRIAM enzyme-specific profiles | 3.4.21.72 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.72 |
IUBMB Enzyme Nomenclature | 3.4.21.72 |
IntEnz | 3.4.21.72 |
MEDLINE | Find literature relating to 3.4.21.72 |
MetaCyc | 3.4.21.72 |
Rhea expert-curated reactions | 3.4.21.72 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-