Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am
CEST. Apologies for the inconvenience.
ENZYME entry: EC 3.4.24.81
Accepted Name |
ADAM10 endopeptidase.
|
Alternative Name(s) |
Kuzbanian protein. |
myelin-associated disintegrin metalloproteinase. |
Reaction catalysed |
Endopeptidase of broad specificity |
Comment(s) |
- Partially responsible for the 'alpha-secretase' activity in brain
that degrades the potentially harmful beta-amyloid peptide.
- Work with ADAM10-deficient mice supports a role in Notch signaling.
- Belongs to peptidase family M12.
|
Cross-references |
BRENDA | 3.4.24.81 |
EC2PDB | 3.4.24.81 |
ExplorEnz | 3.4.24.81 |
PRIAM enzyme-specific profiles | 3.4.24.81 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.81 |
IUBMB Enzyme Nomenclature | 3.4.24.81 |
IntEnz | 3.4.24.81 |
MEDLINE | Find literature relating to 3.4.24.81 |
MetaCyc | 3.4.24.81 |
Rhea expert-curated reactions | 3.4.24.81 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-