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ENZYME

ENZYME entry: EC 3.4.24.82

PURL: https://purl.expasy.org/enzyme/EC/3.4.24.82
Accepted Name
ADAMTS-4 endopeptidase
Alternative Name(s)
aggrecanase-1
Reaction catalysed
Glutamyl endopeptidase. Bonds cleaved include 370-Thr-Glu-Gly-Glu-|-Ala-Arg-Gly-Ser-377 in the interglobular domain of mammalian aggrecan
Comment(s)
  • Thought to be biologically significant for the degradation of the aggrecan component of cartilage matrix.
  • Belongs to peptidase family M12.
Cross-references
BRENDA3.4.24.82
EC2PDB3.4.24.82
ExplorEnz3.4.24.82
KEGG Ligand Database for Enzyme Nomenclature3.4.24.82
IUBMB Enzyme Nomenclature3.4.24.82
MEDLINEFind literature relating to 3.4.24.82
MetaCyc3.4.24.82
Rhea expert-curated reactions3.4.24.82
UniProtKB/Swiss-Prot
Q9TT93, ATS4_BOVINO75173, ATS4_HUMANQ8BNJ2, ATS4_MOUSE
Q5RFQ8, ATS4_PONABQ9ESP7, ATS4_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-