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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
6-aminohexanoate-oligomer endohydrolase.
Alternative Name(s)
6-aminohexanoate oligomer hydrolase.
Endo-type 6-aminohexanoate oligomer hydrolase.
Nylon hydrolase.
Nylon-6 hydrolase.
Nylon-oligomer hydrolase.
Reaction catalysed
(N-(6-aminohexanoyl))(n) + H(2)O <=> (N-(6-aminohexanoyl))(n-x) + (N-(6-aminohexanoyl))(x)
  • The enzyme is involved in degradation of nylon-6 oligomers.
  • It degrades linear or cyclic oligomers of poly(6-aminohexanoate) with a degree of polymerization greater than three (n > 3) by endo-type cleavage, to oligomers of a length of two or more (2 <= x < n).
  • It shows negligible activity with N-(6-aminohexanoyl)-6- aminohexanoate (cf. EC or with 1,8-diazacyclotetradecane- 2,9-dione (cf. EC
PRIAM enzyme-specific profiles3.5.1.117
KEGG Ligand Database for Enzyme Nomenclature3.5.1.117
IUBMB Enzyme Nomenclature3.5.1.117
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