ENZYME entry: EC 3.6.1.56
Accepted Name |
2-hydroxy-dATP diphosphatase.
|
Alternative Name(s) |
(2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase. |
Oxidized purine nucleoside triphosphatase. |
Reaction catalysed |
2-hydroxy-dATP + H(2)O <=> 2-hydroxy-dAMP + diphosphate |
Comment(s) |
- The enzyme hydrolyzes oxidized purine nucleoside triphosphates such
as 2-hydroxy-dATP, thereby preventing their misincorporation into
DNA.
- It can also recognize 8-oxo-dGTP and 8-oxo-dATP, but with lower
efficiency (cf. EC 3.6.1.55).
|
Cross-references |
BRENDA | 3.6.1.56 |
EC2PDB | 3.6.1.56 |
ExplorEnz | 3.6.1.56 |
PRIAM enzyme-specific profiles | 3.6.1.56 |
KEGG Ligand Database for Enzyme Nomenclature | 3.6.1.56 |
IUBMB Enzyme Nomenclature | 3.6.1.56 |
IntEnz | 3.6.1.56 |
MEDLINE | Find literature relating to 3.6.1.56 |
MetaCyc | 3.6.1.56 |
UniProtKB/Swiss-Prot |
|
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