A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.6.1.56
| Accepted Name |
|---|
| 2-hydroxy-dATP diphosphatase.
|
| Alternative Name(s) |
|---|
| (2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase. |
| Oxidized purine nucleoside triphosphatase. |
| Reaction catalysed |
|---|
| 2-hydroxy-dATP + H(2)O <=> 2-hydroxy-dAMP + diphosphate |
| Comment(s) |
|---|
- The enzyme hydrolyzes oxidized purine nucleoside triphosphates such
as 2-hydroxy-dATP, thereby preventing their misincorporation into
DNA.
- It can also recognize 8-oxo-dGTP and 8-oxo-dATP, but with lower
efficiency (cf. EC 3.6.1.55).
|
| Cross-references |
|---|
| BRENDA | 3.6.1.56 |
| EC2PDB | 3.6.1.56 |
| ExplorEnz | 3.6.1.56 |
| PRIAM enzyme-specific profiles | 3.6.1.56 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.6.1.56 |
| IUBMB Enzyme Nomenclature | 3.6.1.56 |
| IntEnz | 3.6.1.56 |
| MEDLINE | Find literature relating to 3.6.1.56 |
| MetaCyc | 3.6.1.56 |
| UniProtKB/Swiss-Prot |
|
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