A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.6.3.10
| Accepted Name |
|---|
| Hydrogen/potassium-exchanging ATPase.
|
| Alternative Name(s) |
|---|
| Gastric H(+)/K(+) ATPase. |
| H(+)/K(+)-ATPase. |
| H(+)/K(+)-exchanging ATPase. |
| Potassium-transporting ATPase. |
| Proton pump. |
| Reaction catalysed |
|---|
| ATP + H(2)O + H(+)(In) + K(+)(Out) <=> ADP + phosphate + H(+)(Out) + K(+)(In) |
| Cofactor(s) |
|---|
| Mg(2+).
|
| Comment(s) |
|---|
- P-type ATPase that undergoes covalent phosphorylation during the
transport cycle.
- Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
- Formerly EC 3.6.1.36.
|
| Cross-references |
|---|
| PROSITE | PDOC00139 |
| BRENDA | 3.6.3.10 |
| EC2PDB | 3.6.3.10 |
| ExplorEnz | 3.6.3.10 |
| PRIAM enzyme-specific profiles | 3.6.3.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.6.3.10 |
| IUBMB Enzyme Nomenclature | 3.6.3.10 |
| IntEnz | 3.6.3.10 |
| MEDLINE | Find literature relating to 3.6.3.10 |
| MetaCyc | 3.6.3.10 |
| UniProtKB/Swiss-Prot |
| Q64392, AT12A_CAVPO; | P54707, AT12A_HUMAN; | Q9Z1W8, AT12A_MOUSE; |
| Q9TV52, AT12A_RABIT; | P54708, AT12A_RAT; | Q92036, AT12A_RHIMB; |
| P50996, ATP4A_CANLF; | P20648, ATP4A_HUMAN; | Q64436, ATP4A_MOUSE; |
| P19156, ATP4A_PIG; | P27112, ATP4A_RABIT; | P09626, ATP4A_RAT; |
| Q92126, ATP4A_XENLA; |
|
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