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ENZYME

ENZYME entry: EC 7.2.2.19

Accepted Name
H(+)/K(+)-exchanging ATPase
Alternative Name(s)
gastric H(+)/K(+) ATPase
H(+)/K(+)-ATPase
potassium-transporting ATPase
proton pump
Reaction catalysed
K(+)(out) + ATP + H2O + H(+)(in) = K(+)(in) + ADP + phosphate + 2 H(+)(out)
Comment(s)
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • A gastric mucosal enzyme that catalyzes the efflux of one H(+) and the influx of one K(+) per ATP hydrolyzed.
  • Formerly EC 3.6.1.36 and EC 3.6.3.10.
Cross-references
BRENDA7.2.2.19
EC2PDB7.2.2.19
ExplorEnz7.2.2.19
KEGG Ligand Database for Enzyme Nomenclature7.2.2.19
IUBMB Enzyme Nomenclature7.2.2.19
MEDLINEFind literature relating to 7.2.2.19
MetaCyc7.2.2.19
Rhea expert-curated reactions7.2.2.19
UniProtKB/Swiss-Prot
Q64392, AT12A_CAVPOP54707, AT12A_HUMANQ9Z1W8, AT12A_MOUSE
Q9TV52, AT12A_RABITP54708, AT12A_RATQ92036, AT12A_RHIMB
P50996, ATP4A_CANLFP20648, ATP4A_HUMANQ64436, ATP4A_MOUSE
P19156, ATP4A_PIGP27112, ATP4A_RABITP09626, ATP4A_RAT
Q92126, ATP4A_XENLA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.2.-
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