ENZYME entry: EC 3.6.5.2
| Accepted Name |
|---|
| Small monomeric GTPase.
|
| Reaction catalysed |
|---|
| GTP + H(2)O <=> GDP + phosphate |
| Comment(s) |
|---|
- A family of about 50 enzymes with a molecular mass of 21 kDa that are
distantly related to the alpha-subunit of EC 3.6.1.46.
- Involved in cell-growth regulation (Ras subfamily), membrane vesicle
traffic and uncoating (Rab and ARF subfamilies), nuclear protein
import (Ran subfamily) and organization of the cytoskeleton (Rho and
Rac subfamilies).
- Formerly EC 3.6.1.47.
|
| Cross-references |
|---|
| PROSITE | PDOC00859 |
| BRENDA | 3.6.5.2 |
| EC2PDB | 3.6.5.2 |
| ExplorEnz | 3.6.5.2 |
| PRIAM enzyme-specific profiles | 3.6.5.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.6.5.2 |
| IUBMB Enzyme Nomenclature | 3.6.5.2 |
| IntEnz | 3.6.5.2 |
| MEDLINE | Find literature relating to 3.6.5.2 |
| MetaCyc | 3.6.5.2 |
| UniProtKB/Swiss-Prot |
|
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