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ENZYME entry: EC 3.7.1.8

Accepted Name
2,6-dioxo-6-phenylhexa-3-enoate hydrolase.
Alternative Name(s)
HOHPDA hydrolase.
Reaction catalysed
2,6-dioxo-6-phenylhexa-3-enoate + H2O <=> 2-oxopent-4-enoate + benzoate + H(+)
Comment(s)
  • Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 by ring-fission at a -CO-C bond.
  • Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.
Cross-references
BRENDA3.7.1.8
EC2PDB3.7.1.8
ExplorEnz3.7.1.8
PRIAM enzyme-specific profiles3.7.1.8
KEGG Ligand Database for Enzyme Nomenclature3.7.1.8
IUBMB Enzyme Nomenclature3.7.1.8
IntEnz3.7.1.8
MEDLINEFind literature relating to 3.7.1.8
MetaCyc3.7.1.8
Rhea expert-curated reactions3.7.1.8
UniProtKB/Swiss-Prot
Q2VLB9, BPHD_BURCE;  Q59324, BPHD_COMTE;  Q8KRD3, BPHD_DELAC;  
P47229, BPHD_PARXL;  A1VUV0, BPHD_POLNA;  Q52011, BPHD_PSEFK;  
Q52036, BPHD_PSEPU;  P17548, BPHD_PSES1;  P9WNH4, HSAD_MYCTO;  
P9WNH5, HSAD_MYCTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.-.-
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