ENZYME entry: EC 3.8.1.10
| Accepted Name |
|---|
| 2-haloacid dehalogenase (configuration-inverting).
|
| Alternative Name(s) |
|---|
| 2-haloalkanoic acid dehalogenase. |
| 2-haloalkanoid acid halidohydrolase. |
| DL-2-haloacid dehalogenase. |
| DL-2-haloacid dehalogenase (inversion of configuration). |
| DL-2-haloacid halidohydrolase (inversion of configuration). |
| DL-DEXi. |
| Reaction catalysed |
|---|
- (S)-2-haloacid + H(2)O <=> (R)-2-hydroxyacid + halide
- (R)-2-haloacid + H(2)O <=> (S)-2-hydroxyacid + halide
|
| Comment(s) |
|---|
- Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with
inversion of configuration at C-2.
- The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids
whose carbon chain lengths are five or less (see also EC 3.8.1.2,
EC 3.8.1.9 and EC 3.8.1.11).
|
| Cross-references |
|---|
| BRENDA | 3.8.1.10 |
| EC2PDB | 3.8.1.10 |
| ExplorEnz | 3.8.1.10 |
| PRIAM enzyme-specific profiles | 3.8.1.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.8.1.10 |
| IUBMB Enzyme Nomenclature | 3.8.1.10 |
| IntEnz | 3.8.1.10 |
| MEDLINE | Find literature relating to 3.8.1.10 |
| MetaCyc | 3.8.1.10 |
| UniProtKB/Swiss-Prot |
|
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