ENZYME entry: EC 3.8.1.11
Accepted Name |
2-haloacid dehalogenase (configuration-retaining).
|
Alternative Name(s) |
2-haloalkanoic acid dehalogenase. |
2-haloalkanoid acid halidohydrolase. |
DL-2-haloacid dehalogenase. |
DL-DEXr. |
Reaction catalysed |
- an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)
- an (R)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)
|
Comment(s) |
Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with
retention of configuration at C-2 (see also EC 3.8.1.2, EC 3.8.1.9
and EC 3.8.1.10).
|
Cross-references |
BRENDA | 3.8.1.11 |
EC2PDB | 3.8.1.11 |
ExplorEnz | 3.8.1.11 |
PRIAM enzyme-specific profiles | 3.8.1.11 |
KEGG Ligand Database for Enzyme Nomenclature | 3.8.1.11 |
IUBMB Enzyme Nomenclature | 3.8.1.11 |
IntEnz | 3.8.1.11 |
MEDLINE | Find literature relating to 3.8.1.11 |
MetaCyc | 3.8.1.11 |
Rhea expert-curated reactions | 3.8.1.11 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.8.1.-
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