ENZYME entry: EC 3.8.1.11
| Accepted Name |
|---|
| 2-haloacid dehalogenase (configuration-retaining).
|
| Alternative Name(s) |
|---|
| 2-haloalkanoic acid dehalogenase. |
| 2-haloalkanoid acid halidohydrolase. |
| DL-2-haloacid dehalogenase. |
| DL-DEXr. |
| Reaction catalysed |
|---|
- an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)
- an (R)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)
|
| Comment(s) |
|---|
| Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with
retention of configuration at C-2 (see also EC 3.8.1.2, EC 3.8.1.9
and EC 3.8.1.10).
|
| Cross-references |
|---|
| BRENDA | 3.8.1.11 |
| EC2PDB | 3.8.1.11 |
| ExplorEnz | 3.8.1.11 |
| PRIAM enzyme-specific profiles | 3.8.1.11 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.8.1.11 |
| IUBMB Enzyme Nomenclature | 3.8.1.11 |
| IntEnz | 3.8.1.11 |
| MEDLINE | Find literature relating to 3.8.1.11 |
| MetaCyc | 3.8.1.11 |
| Rhea expert-curated reactions | 3.8.1.11 |
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