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ENZYME

ENZYME entry: EC 3.8.1.11

PURL: https://purl.expasy.org/enzyme/EC/3.8.1.11
Accepted Name
2-haloacid dehalogenase (configuration-retaining)
Alternative Name(s)
2-haloalkanoic acid dehalogenase
2-haloalkanoid acid halidohydrolase
DL-2-haloacid dehalogenase
DL-DEXr
Reaction catalysed
  • an (S)-2-haloacid + H2O = a (2S)-2-hydroxycarboxylate + a halide anion + H(+)
  • an (R)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)
Comment(s)
Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with retention of configuration at C-2 (see also EC 3.8.1.2, EC 3.8.1.9 and EC 3.8.1.10).
Cross-references
BRENDA3.8.1.11
EC2PDB3.8.1.11
ExplorEnz3.8.1.11
KEGG Ligand Database for Enzyme Nomenclature3.8.1.11
IUBMB Enzyme Nomenclature3.8.1.11
MEDLINEFind literature relating to 3.8.1.11
MetaCyc3.8.1.11
Rhea expert-curated reactions3.8.1.11

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-