ENZYME entry: EC 4.2.2.2

PURL: https://purl.expasy.org/enzyme/EC/4.2.2.2

Accepted Name

pectate lyase

Alternative Name(s)

alpha-1,4-D-endopolygalacturonic acid lyase

endo-alpha-1,4-polygalacturonic acid lyase

endogalacturonate transeliminase

endopectin methyltranseliminase

pectate transeliminase

pectic acid lyase

pectic acid transeliminase

pectic lyase

pectin trans-eliminase

PGA lyase

polygalacturonate lyase

polygalacturonic acid lyase

polygalacturonic acid trans-eliminase

polygalacturonic transeliminase

PPase-N

Reaction catalysed

Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends

Comment(s)

Favors pectate, the anion, over pectin, the methyl ester (which is the preferred substrate of EC 4.2.2.10).
Formerly EC 4.2.99.3.

Cross-references

BRENDA

4.2.2.2

EC2PDB

4.2.2.2

ExplorEnz

4.2.2.2

KEGG Ligand Database for Enzyme Nomenclature

4.2.2.2

IUBMB Enzyme Nomenclature

4.2.2.2

MEDLINE

Find literature relating to 4.2.2.2

MetaCyc

4.2.2.2

Rhea expert-curated reactions

4.2.2.2

UniProtKB/Swiss-Prot

Q9LJ42, PLY10_ARATH	Q9LTZ0, PLY11_ARATH	Q9SCP2, PLY12_ARATH
Q93Z04, PLY13_ARATH	Q9SVQ6, PLY14_ARATH	Q944R1, PLY15_ARATH
O65456, PLY16_ARATH	O65457, PLY17_ARATH	Q9C5M8, PLY18_ARATH
P24396, PLY18_SOLLC	Q9LFP5, PLY19_ARATH	P27760, PLY1_AMBAR
Q940Q1, PLY1_ARATH	Q96385, PLY1_CHAOB	P18632, PLY1_CRYJA
Q9SCG9, PLY1_HESAR	P81294, PLY1_JUNAS	Q9LLT1, PLY1_JUNVI
Q6CZT4, PLY1_PECAS	P0C1C0, PLY1_PECCA	Q93WF1, PLY20_ARATH
Q9FM66, PLY21_ARATH	Q93Z25, PLY22_ARATH	P27761, PLY2_AMBAR
O65388, PLY2_ARATH	Q6CZT3, PLY2_PECAS	P0C1C1, PLY2_PECCA
P28744, PLY3_AMBAR	Q9M9S2, PLY3_ARATH	Q6CZT2, PLY3_PECAS
P0C1C2, PLY3_PECCA	P0C1C3, PLY3_PECCC	P27762, PLY4_AMBAR
Q9C8G4, PLY4_ARATH	P15721, PLY56_SOLLC	P15722, PLY59_SOLLC
P27759, PLY5_AMBAR	Q9FXD8, PLY5_ARATH	O64510, PLY6_ARATH
Q9SRH4, PLY7_ARATH	Q9M8Z8, PLY8_ARATH	Q9LRM5, PLY9_ARATH
B0XT32, PLYA_ASPFC	B8NE46, PLYA_ASPFN	Q4WIT0, PLYA_ASPFU
A2QV36, PLYA_ASPNC	Q9C2Z0, PLYA_ASPNG	Q2U8R6, PLYA_ASPOR
P0C1A2, PLYA_DICCH	P0C1A3, PLYA_DICD3	Q5AVN4, PLYA_EMENI
A1CYB8, PLYA_NEOFI	D3JTC1, PLYA_PAEAM	Q9X6Z2, PLYA_PAEBA
A7E4L6, PLYA_SCLS1	B8NBC2, PLYB_ASPFN	Q2TZY0, PLYB_ASPOR
Q0CBV0, PLYB_ASPTN	O59939, PLYB_COLGL	P04959, PLYB_DICCH
Q00645, PLYB_EMENI	D3JTC2, PLYB_PAEAM	B0XMA2, PLYC_ASPFC
B8NQQ7, PLYC_ASPFN	Q4WL88, PLYC_ASPFU	Q2UB83, PLYC_ASPOR
Q0CLG7, PLYC_ASPTN	Q65EF5, PLYC_BACLD	O34310, PLYC_BACSU
P11073, PLYC_DICCH	Q5B297, PLYC_EMENI	A1DPF0, PLYC_NEOFI
B0YB89, PLYD_ASPFC	Q4WGV9, PLYD_ASPFU	Q0CJ49, PLYD_ASPTN
P18209, PLYD_DICCH	Q5BA88, PLYD_EMENI	A1DCY5, PLYD_NEOFI
P04960, PLYE1_DICCH	P0C1A4, PLYE2_DICCH	A1C4B8, PLYE_ASPCL
B0Y9M8, PLYE_ASPFC	B8NX10, PLYE_ASPFN	Q4WC29, PLYE_ASPFU
Q2TW49, PLYE_ASPOR	P0C1A5, PLYE_DICD3	Q5B7Z3, PLYE_EMENI
A1DBJ7, PLYE_NEOFI	B0Y953, PLYF_ASPFC	B8NJZ7, PLYF_ASPFN
Q4WKV8, PLYF_ASPFU	Q0CCF8, PLYF_ASPTN	Q5B024, PLYF_EMENI
A1D5E3, PLYF_NEOFI	Q0CJ20, PLYG_ASPTN	Q5AY82, PLYG_EMENI
Q5ATC7, PLYH_EMENI	P0C1A6, PLYL_DICCH	P0C1A7, PLYL_DICD3
Q5BA93, PLYL_EMENI	E3E7F9, PLYL_PAEPS	Q76EC9, PLYL_THEST
P14005, PLYP_PECCC	P11278, PLYP_YERPS	P16530, PLYX_PECCA
P39116, PLY_BACSU	P40973, PLY_LILLO	P72242, PLY_PSEAV
Q59671, PLY_PSEFL	Q51915, PLY_PSEMA	Q60140, PLY_PSEVI
P40972, PLY_TOBAC	Q56806, PLY_XANCM	O24554, PLY_ZINEL

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-