A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
Lyases
The following ENZYME entries belong to class 4.-.-.-:
4.1.1.1 Pyruvate decarboxylase 4.1.1.2 Oxalate decarboxylase 4.1.1.3 Transferred entry: 4.1.1.112 4.1.1.4 Acetoacetate decarboxylase 4.1.1.5 Acetolactate decarboxylase 4.1.1.6 Aconitate decarboxylase 4.1.1.7 Benzoylformate decarboxylase 4.1.1.8 Oxalyl-CoA decarboxylase 4.1.1.9 Malonyl-CoA decarboxylase 4.1.1.10 Transferred entry: 4.1.1.12 4.1.1.11 Aspartate 1-decarboxylase 4.1.1.12 Aspartate 4-decarboxylase 4.1.1.13 Deleted entry 4.1.1.14 Valine decarboxylase 4.1.1.15 Glutamate decarboxylase 4.1.1.16 Hydroxyglutamate decarboxylase 4.1.1.17 Ornithine decarboxylase 4.1.1.18 Lysine decarboxylase 4.1.1.19 Arginine decarboxylase 4.1.1.20 Diaminopimelate decarboxylase 4.1.1.21 Phosphoribosylaminoimidazole carboxylase 4.1.1.22 Histidine decarboxylase 4.1.1.23 Orotidine-5'-phosphate decarboxylase 4.1.1.24 Aminobenzoate decarboxylase 4.1.1.25 Tyrosine decarboxylase 4.1.1.26 Transferred entry: 4.1.1.28 4.1.1.27 Transferred entry: 4.1.1.28 4.1.1.28 Aromatic-L-amino-acid decarboxylase 4.1.1.29 Sulfinoalanine decarboxylase 4.1.1.30 Pantothenoylcysteine decarboxylase 4.1.1.31 Phosphoenolpyruvate carboxylase 4.1.1.32 Phosphoenolpyruvate carboxykinase (GTP) 4.1.1.33 Diphosphomevalonate decarboxylase 4.1.1.34 Dehydro-L-gulonate decarboxylase 4.1.1.35 UDP-glucuronate decarboxylase 4.1.1.36 Phosphopantothenoylcysteine decarboxylase 4.1.1.37 Uroporphyrinogen decarboxylase 4.1.1.38 Phosphoenolpyruvate carboxykinase (diphosphate) 4.1.1.39 Ribulose-bisphosphate carboxylase 4.1.1.40 Hydroxypyruvate decarboxylase 4.1.1.41 Transferred entry: 7.2.4.3 4.1.1.42 Carnitine decarboxylase 4.1.1.43 Phenylpyruvate decarboxylase 4.1.1.44 4-carboxymuconolactone decarboxylase 4.1.1.45 Aminocarboxymuconate-semialdehyde decarboxylase 4.1.1.46 o-pyrocatechuate decarboxylase 4.1.1.47 Tartronate-semialdehyde synthase 4.1.1.48 Indole-3-glycerol-phosphate synthase 4.1.1.49 Phosphoenolpyruvate carboxykinase (ATP) 4.1.1.50 Adenosylmethionine decarboxylase 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase 4.1.1.52 6-methylsalicylate decarboxylase 4.1.1.53 Phenylalanine decarboxylase 4.1.1.54 Dihydroxyfumarate decarboxylase 4.1.1.55 4,5-dihydroxyphthalate decarboxylase 4.1.1.56 3-oxolaurate decarboxylase 4.1.1.57 Methionine decarboxylase 4.1.1.58 Orsellinate decarboxylase 4.1.1.59 Gallate decarboxylase 4.1.1.60 Stipitatonate decarboxylase 4.1.1.61 4-hydroxybenzoate decarboxylase 4.1.1.62 Gentisate decarboxylase 4.1.1.63 Protocatechuate decarboxylase 4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate) 4.1.1.65 Phosphatidylserine decarboxylase 4.1.1.66 Uracil-5-carboxylate decarboxylase 4.1.1.67 UDP-galacturonate decarboxylase 4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 4.1.1.69 3,4-dihydroxyphthalate decarboxylase 4.1.1.70 Glutaconyl-CoA decarboxylase 4.1.1.71 2-oxoglutarate decarboxylase 4.1.1.72 Branched-chain-2-oxoacid decarboxylase 4.1.1.73 Tartrate decarboxylase 4.1.1.74 Indolepyruvate decarboxylase 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase 4.1.1.76 Arylmalonate decarboxylase 4.1.1.77 2-oxo-3-hexenedioate decarboxylase 4.1.1.78 Acetylenedicarboxylate decarboxylase 4.1.1.79 Sulfopyruvate decarboxylase 4.1.1.80 4-hydroxyphenylpyruvate decarboxylase 4.1.1.81 Threonine-phosphate decarboxylase 4.1.1.82 Phosphonopyruvate decarboxylase 4.1.1.83 4-hydroxyphenylacetate decarboxylase 4.1.1.84 D-dopachrome decarboxylase 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase 4.1.1.86 Diaminobutyrate decarboxylase 4.1.1.87 Malonyl-S-ACP decarboxylase 4.1.1.88 Biotin-independent malonate decarboxylase 4.1.1.89 Biotin-dependent malonate decarboxylase 4.1.1.90 Peptidyl-glutamate 4-carboxylase 4.1.1.91 Salicylate decarboxylase 4.1.1.92 Indole-3-carboxylate decarboxylase 4.1.1.93 Pyrrole-2-carboxylate decarboxylase 4.1.1.94 Ethylmalonyl-CoA decarboxylase 4.1.1.95 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase 4.1.1.96 Carboxynorspermidine decarboxylase 4.1.1.97 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase 4.1.1.98 4-hydroxy-3-polyprenylbenzoate decarboxylase 4.1.1.99 Phosphomevalonate decarboxylase 4.1.1.100 Prephenate decarboxylase 4.1.1.101 Malolactic enzyme 4.1.1.102 Phenacrylate decarboxylase 4.1.1.103 Gamma-resorcylate decarboxylase 4.1.1.104 3-dehydro-4-phosphotetronate decarboxylase 4.1.1.105 L-tryptophan decarboxylase 4.1.1.106 Fatty acid photodecarboxylase 4.1.1.107 3,4-dihydroxyphenylacetaldehyde synthase 4.1.1.108 4-hydroxyphenylacetaldehyde synthase 4.1.1.109 Phenylacetaldehyde synthase 4.1.1.110 Bisphosphomevalonate decarboxylase 4.1.1.111 Siroheme decarboxylase 4.1.1.112 Oxaloacetate decarboxylase 4.1.1.n1 Transferred entry: 4.1.1.97 4.1.1.n2 Transferred entry: 4.1.1.94 4.1.2.1 Transferred entry: 4.1.3.16 4.1.2.2 Ketotetrose-phosphate aldolase 4.1.2.3 Deleted entry 4.1.2.4 Deoxyribose-phosphate aldolase 4.1.2.5 L-threonine aldolase 4.1.2.6 Deleted entry 4.1.2.7 Transferred entry: 4.1.2.13 4.1.2.8 Indole-3-glycerol-phosphate lyase 4.1.2.9 Phosphoketolase 4.1.2.10 (R)-mandelonitrile lyase 4.1.2.11 Hydroxymandelonitrile lyase 4.1.2.12 2-dehydropantoate aldolase 4.1.2.13 Fructose-bisphosphate aldolase 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase 4.1.2.15 Transferred entry: 2.5.1.54 4.1.2.16 Transferred entry: 2.5.1.55 4.1.2.17 L-fuculose-phosphate aldolase 4.1.2.18 2-dehydro-3-deoxy-L-pentonate aldolase 4.1.2.19 Rhamnulose-1-phosphate aldolase 4.1.2.20 2-dehydro-3-deoxyglucarate aldolase 4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4.1.2.22 Fructose-6-phosphate phosphoketolase 4.1.2.23 3-deoxy-D-manno-octulosonate aldolase 4.1.2.24 Dimethylaniline-N-oxide aldolase 4.1.2.25 Dihydroneopterin aldolase 4.1.2.26 Phenylserine aldolase 4.1.2.27 Sphinganine-1-phosphate aldolase 4.1.2.28 2-dehydro-3-deoxy-D-pentonate aldolase 4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase 4.1.2.30 Transferred entry: 1.14.14.32 4.1.2.31 Transferred entry: 4.1.3.16 4.1.2.32 Trimethylamine-oxide aldolase 4.1.2.33 Fucosterol-epoxide lyase 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase 4.1.2.35 Propioin synthase 4.1.2.36 Lactate aldolase 4.1.2.37 Transferred entry: 4.1.2.46 and 4.1.2.47 4.1.2.38 Benzoin aldolase 4.1.2.39 Transferred entry: 4.1.2.46 and 4.1.2.47 4.1.2.40 Tagatose-bisphosphate aldolase 4.1.2.41 Vanillin synthase 4.1.2.42 D-threonine aldolase 4.1.2.43 3-hexulose-6-phosphate synthase 4.1.2.44 2,3-epoxybenzoyl-CoA dihydrolase 4.1.2.45 Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase 4.1.2.46 Aliphatic (R)-hydroxynitrile lyase 4.1.2.47 (S)-hydroxynitrile lyase 4.1.2.48 Low-specificity L-threonine aldolase 4.1.2.49 L-allo-threonine aldolase 4.1.2.50 6-carboxytetrahydropterin synthase 4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase 4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase 4.1.2.53 2-keto-3-deoxy-L-rhamnonate aldolase 4.1.2.54 L-threo-3-deoxy-hexylosonate aldolase 4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4.1.2.56 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate synthase 4.1.2.57 Sulfofructosephosphate aldolase 4.1.2.58 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase 4.1.2.59 Dihydroneopterin phosphate aldolase 4.1.2.60 Dihydroneopterin triphosphate aldolase 4.1.2.n1 Transferred entry: 4.1.2.44 4.1.2.n2 2-hydroxyphytanoyl-CoA lyase 4.1.2.n3 Transferred entry: 4.1.2.53 4.1.2.n4 Transferred entry: 4.1.2.52 4.1.2.n5 Transferred entry: 2.2.1.10 4.1.2.n6 Transferred entry: 4.1.2.56 4.1.3.1 Isocitrate lyase 4.1.3.2 Transferred entry: 2.3.3.9 4.1.3.3 N-acetylneuraminate lyase 4.1.3.4 Hydroxymethylglutaryl-CoA lyase 4.1.3.5 Transferred entry: 2.3.3.10 4.1.3.6 Citrate (pro-3S)-lyase 4.1.3.7 Transferred entry: 2.3.3.1 4.1.3.8 Transferred entry: 2.3.3.8 4.1.3.9 Transferred entry: 2.3.3.11 4.1.3.10 Transferred entry: 2.3.3.7 4.1.3.11 Transferred entry: 2.3.3.12 4.1.3.12 Transferred entry: 2.3.3.13 4.1.3.13 Oxalomalate lyase 4.1.3.14 L-erythro-3-hydroxyaspartate aldolase 4.1.3.15 Transferred entry: 2.2.1.5 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase 4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase 4.1.3.18 Transferred entry: 2.2.1.6 4.1.3.19 Transferred entry: 2.5.1.56 4.1.3.20 Transferred entry: 2.5.1.57 4.1.3.21 Transferred entry: 2.3.3.14 4.1.3.22 Citramalate lyase 4.1.3.23 Transferred entry: 2.3.3.2 4.1.3.24 Malyl-CoA lyase 4.1.3.25 (S)-citramalyl-CoA lyase 4.1.3.26 3-hydroxy-3-isohexenylglutaryl-CoA lyase 4.1.3.27 Anthranilate synthase 4.1.3.28 Transferred entry: 2.3.3.3 4.1.3.29 Transferred entry: 2.3.3.4 4.1.3.30 Methylisocitrate lyase 4.1.3.31 Transferred entry: 2.3.3.5 4.1.3.32 2,3-dimethylmalate lyase 4.1.3.33 Transferred entry: 2.3.3.6 4.1.3.34 Citryl-CoA lyase 4.1.3.35 (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase 4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase 4.1.3.37 Transferred entry: 2.2.1.7 4.1.3.38 Aminodeoxychorismate lyase 4.1.3.39 4-hydroxy-2-oxovalerate aldolase 4.1.3.40 Chorismate lyase 4.1.3.41 3-hydroxy-D-aspartate aldolase 4.1.3.42 (4S)-4-hydroxy-2-oxoglutarate aldolase 4.1.3.43 4-hydroxy-2-oxohexanoate aldolase 4.1.3.44 tRNA 4-demethylwyosine synthase (AdoMet-dependent) 4.1.3.45 3-hydroxybenzoate synthase 4.1.3.46 (R)-citramalyl-CoA lyase 4.1.3.n1 Transferred entry: 4.1.3.43 4.1.99.1 Tryptophanase 4.1.99.2 Tyrosine phenol-lyase 4.1.99.3 Deoxyribodipyrimidine photo-lyase 4.1.99.4 Transferred entry: 3.5.99.7 4.1.99.5 Aldehyde oxygenase (deformylating) 4.1.99.6 Transferred entry: 4.2.3.6 4.1.99.7 Transferred entry: 4.2.3.9 4.1.99.8 Transferred entry: 4.2.3.119 and 4.2.3.120 4.1.99.9 Transferred entry: 4.2.3.15 4.1.99.10 Transferred entry: 4.2.3.16 4.1.99.11 Benzylsuccinate synthase 4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase 4.1.99.13 (6-4)DNA photolyase 4.1.99.14 Spore photoproduct lyase 4.1.99.15 Deleted entry 4.1.99.16 Geosmin synthase 4.1.99.17 Phosphomethylpyrimidine synthase 4.1.99.18 Transferred entry: 4.1.99.22 and 4.6.1.17 4.1.99.19 2-iminoacetate synthase 4.1.99.20 3-amino-4-hydroxybenzoate synthase 4.1.99.21 Transferred entry: 4.2.3.153 4.1.99.22 GTP 3',8-cyclase 4.1.99.23 5-hydroxybenzimidazole synthase 4.1.99.24 L-tyrosine isonitrile synthase 4.1.99.25 L-tryptophan isonitrile synthase 4.2.1.1 Carbonic anhydrase 4.2.1.2 Fumarate hydratase 4.2.1.3 Aconitate hydratase 4.2.1.4 Transferred entry: 4.2.1.3 4.2.1.5 Arabinonate dehydratase 4.2.1.6 Galactonate dehydratase 4.2.1.7 Altronate dehydratase 4.2.1.8 Mannonate dehydratase 4.2.1.9 Dihydroxy-acid dehydratase 4.2.1.10 3-dehydroquinate dehydratase 4.2.1.11 Phosphopyruvate hydratase 4.2.1.12 Phosphogluconate dehydratase 4.2.1.13 Transferred entry: 4.3.1.17 4.2.1.14 Transferred entry: 4.3.1.18 4.2.1.15 Transferred entry: 4.4.1.1 4.2.1.16 Transferred entry: 4.3.1.19 4.2.1.17 Enoyl-CoA hydratase 4.2.1.18 Methylglutaconyl-CoA hydratase 4.2.1.19 Imidazoleglycerol-phosphate dehydratase 4.2.1.20 Tryptophan synthase 4.2.1.21 Transferred entry: 4.2.1.22 4.2.1.22 Cystathionine beta-synthase 4.2.1.23 Deleted entry 4.2.1.24 Porphobilinogen synthase 4.2.1.25 L-arabinonate dehydratase 4.2.1.26 Transferred entry: 4.3.1.9 4.2.1.27 Acetylenecarboxylate hydratase 4.2.1.28 Propanediol dehydratase 4.2.1.29 Transferred entry: 4.99.1.6 4.2.1.30 Glycerol dehydratase 4.2.1.31 Maleate hydratase 4.2.1.32 L(+)-tartrate dehydratase 4.2.1.33 3-isopropylmalate dehydratase 4.2.1.34 (S)-2-methylmalate dehydratase 4.2.1.35 (R)-2-methylmalate dehydratase 4.2.1.36 Homoaconitate hydratase 4.2.1.37 Transferred entry: 3.3.2.4 4.2.1.38 Transferred entry: 4.3.1.20 4.2.1.39 Gluconate dehydratase 4.2.1.40 Glucarate dehydratase 4.2.1.41 5-dehydro-4-deoxyglucarate dehydratase 4.2.1.42 Galactarate dehydratase 4.2.1.43 2-dehydro-3-deoxy-L-arabinonate dehydratase 4.2.1.44 Myo-inosose-2 dehydratase 4.2.1.45 CDP-glucose 4,6-dehydratase 4.2.1.46 dTDP-glucose 4,6-dehydratase 4.2.1.47 GDP-mannose 4,6-dehydratase 4.2.1.48 D-glutamate cyclase 4.2.1.49 Urocanate hydratase 4.2.1.50 Pyrazolylalanine synthase 4.2.1.51 Prephenate dehydratase 4.2.1.52 Transferred entry: 4.3.3.7 4.2.1.53 Oleate hydratase 4.2.1.54 Lactoyl-CoA dehydratase 4.2.1.55 3-hydroxybutyryl-CoA dehydratase 4.2.1.56 Itaconyl-CoA hydratase 4.2.1.57 Isohexenylglutaconyl-CoA hydratase 4.2.1.58 Transferred entry: 4.2.1.59 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase 4.2.1.60 Transferred entry: 4.2.1.59 4.2.1.61 Transferred entry: 4.2.1.59 4.2.1.62 5-alpha-hydroxysteroid dehydratase 4.2.1.63 Transferred entry: 3.3.2.9 and 3.3.2.10 4.2.1.64 Transferred entry: 3.3.2.9 and 3.3.2.10 4.2.1.65 3-cyanoalanine hydratase 4.2.1.66 Cyanide hydratase 4.2.1.67 D-fuconate dehydratase 4.2.1.68 L-fuconate dehydratase 4.2.1.69 Cyanamide hydratase 4.2.1.70 Pseudouridylate synthase 4.2.1.71 Transferred entry: 4.2.1.27 4.2.1.72 Transferred entry: 4.1.1.78 4.2.1.73 Protoaphin-aglucone dehydratase (cyclizing) 4.2.1.74 Long-chain-enoyl-CoA hydratase 4.2.1.75 Uroporphyrinogen-III synthase 4.2.1.76 UDP-glucose 4,6-dehydratase 4.2.1.77 Trans-L-3-hydroxyproline dehydratase 4.2.1.78 (S)-norcoclaurine synthase 4.2.1.79 2-methylcitrate dehydratase 4.2.1.80 2-oxopent-4-enoate hydratase 4.2.1.81 D(-)-tartrate dehydratase 4.2.1.82 Xylonate dehydratase 4.2.1.83 4-oxalmesaconate hydratase 4.2.1.84 Nitrile hydratase 4.2.1.85 Dimethylmaleate hydratase 4.2.1.86 Transferred entry: 4.2.1.98 4.2.1.87 Octopamine dehydratase 4.2.1.88 (R)-synephrine 4.2.1.89 Transferred entry: 2.8.3.21 and 4.2.1.149 4.2.1.90 L-rhamnonate dehydratase 4.2.1.91 Arogenate dehydratase 4.2.1.92 Hydroperoxide dehydratase 4.2.1.93 ATP-dependent NAD(P)H-hydrate dehydratase 4.2.1.94 Scytalone dehydratase 4.2.1.95 Kievitone hydratase 4.2.1.96 4a-hydroxytetrahydrobiopterin dehydratase 4.2.1.97 Phaseollidin hydratase 4.2.1.98 16-alpha-hydroxyprogesterone dehydratase 4.2.1.99 2-methylisocitrate dehydratase 4.2.1.100 Cyclohexa-1,5-dienecarbonyl-CoA hydratase 4.2.1.101 Trans-feruloyl-CoA hydratase 4.2.1.102 Transferred entry: 4.2.1.100 4.2.1.103 Cyclohexyl-isocyanide hydratase 4.2.1.104 Cyanase 4.2.1.105 2-hydroxyisoflavanone dehydratase 4.2.1.106 Bile-acid 7-alpha-dehydratase 4.2.1.107 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase 4.2.1.108 Ectoine synthase 4.2.1.109 Methylthioribulose 1-phosphate dehydratase 4.2.1.110 Aldos-2-ulose dehydratase 4.2.1.111 1,5-anhydro-D-fructose dehydratase 4.2.1.112 Acetylene hydratase 4.2.1.113 o-succinylbenzoate synthase 4.2.1.114 Methanogen homoaconitase 4.2.1.115 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4.2.1.116 3-hydroxypropionyl-CoA dehydratase 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) 4.2.1.118 3-dehydroshikimate dehydratase 4.2.1.119 Enoyl-CoA hydratase 2 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase 4.2.1.121 Colneleate synthase 4.2.1.122 Tryptophan synthase (indole-salvaging) 4.2.1.123 Tetrahymanol synthase 4.2.1.124 Arabidiol synthase 4.2.1.125 Dammarenediol II synthase 4.2.1.126 N-acetylmuramic acid 6-phosphate etherase 4.2.1.127 Linalool dehydratase 4.2.1.128 Lupan-3-beta,20-diol synthase 4.2.1.129 Squalene--hopanol cyclase 4.2.1.130 D-lactate dehydratase 4.2.1.131 Carotenoid 1,2-hydratase 4.2.1.132 2-hydroxyhexa-2,4-dienoate hydratase 4.2.1.133 Copal-8-ol diphosphate hydratase 4.2.1.134 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4.2.1.135 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) 4.2.1.136 ADP-dependent NAD(P)H-hydrate dehydratase 4.2.1.137 Sporulenol synthase 4.2.1.138 (+)-caryolan-1-ol synthase 4.2.1.139 Medicarpin synthase 4.2.1.140 Gluconate/galactonate dehydratase 4.2.1.141 2-dehydro-3-deoxy-D-arabinonate dehydratase 4.2.1.142 5'-oxoaverantin cyclase 4.2.1.143 Versicolorin B synthase 4.2.1.144 3-amino-5-hydroxybenzoate synthase 4.2.1.145 Capreomycidine synthase 4.2.1.146 L-galactonate dehydratase 4.2.1.147 5,6,7,8-tetrahydromethanopterin hydro-lyase 4.2.1.148 2-methylfumaryl-CoA hydratase 4.2.1.149 Crotonobetainyl-CoA hydratase 4.2.1.150 Short-chain-enoyl-CoA hydratase 4.2.1.151 Chorismate dehydratase 4.2.1.152 Hydroperoxy icosatetraenoate dehydratase 4.2.1.153 3-methylfumaryl-CoA hydratase 4.2.1.154 Tetracenomycin F2 cyclase 4.2.1.155 Methylthioacryloyl-CoA hydratase 4.2.1.156 L-talarate dehydratase 4.2.1.157 (R)-2-hydroxyisocaproyl-CoA dehydratase 4.2.1.158 Galactarate dehydratase (D-threo-forming) 4.2.1.159 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase 4.2.1.160 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase 4.2.1.161 Bisanhydrobacterioruberin hydratase 4.2.1.162 6-deoxy-6-sulfo-D-gluconate dehydratase 4.2.1.163 2-oxo-hept-4-ene-1,7-dioate hydratase 4.2.1.164 dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase 4.2.1.165 Chlorophyllide a 3(1)-hydratase 4.2.1.166 Phosphinomethylmalate isomerase 4.2.1.167 (R)-2-hydroxyglutaryl-CoA dehydratase 4.2.1.168 GDP-4-dehydro-6-deoxy-alpha-D-mannose 3-dehydratase 4.2.1.169 3-vinylbacteriochlorophyllide d 3(1)-hydratase 4.2.1.170 2-(omega-methylthio)alkylmalate dehydratase 4.2.1.171 Cis-l-3-hydroxyproline dehydratase 4.2.1.172 Trans-4-hydroxy-L-proline dehydratase 4.2.1.173 Ent-8-alpha-hydroxylabd-13-en-15-yl diphosphate synthase 4.2.1.174 Peregrinol diphosphate synthase 4.2.1.n1 Transferred entry: 4.2.1.126 4.2.1.n2 Transferred entry: 4.2.1.134 4.2.2.1 Hyaluronate lyase 4.2.2.2 Pectate lyase 4.2.2.3 Mannuronate-specific alginate lyase 4.2.2.4 Transferred entry: 4.2.2.20 and 4.2.2.21 4.2.2.5 Chondroitin AC lyase 4.2.2.6 Oligogalacturonide lyase 4.2.2.7 Heparin lyase 4.2.2.8 Heparin-sulfate lyase 4.2.2.9 Pectate disaccharide-lyase 4.2.2.10 Pectin lyase 4.2.2.11 Guluronate-specific alginate lyase 4.2.2.12 Xanthan lyase 4.2.2.13 Exo-(1->4)-alpha-D-glucan lyase 4.2.2.14 Glucuronan lyase 4.2.2.15 Anhydrosialidase 4.2.2.16 Levan fructotransferase (DFA-IV-forming) 4.2.2.17 Inulin fructotransferase (DFA-I-forming) 4.2.2.18 Inulin fructotransferase (DFA-III-forming) 4.2.2.19 Chondroitin B lyase 4.2.2.20 Chondroitin-sulfate-ABC endolyase 4.2.2.21 Chondroitin-sulfate-ABC exolyase 4.2.2.22 Pectate trisaccharide-lyase 4.2.2.23 Rhamnogalacturonan endolyase 4.2.2.24 Rhamnogalacturonan exolyase 4.2.2.25 Gellan lyase 4.2.2.26 Oligo-alginate lyase 4.2.2.n1 Peptidoglycan lytic exotransglycosylase 4.2.2.n2 Peptidoglycan lytic endotransglycosylase 4.2.3.1 Threonine synthase 4.2.3.2 Ethanolamine-phosphate phospho-lyase 4.2.3.3 Methylglyoxal synthase 4.2.3.4 3-dehydroquinate synthase 4.2.3.5 Chorismate synthase 4.2.3.6 Trichodiene synthase 4.2.3.7 Pentalenene synthase 4.2.3.8 Casbene synthase 4.2.3.9 Aristolochene synthase 4.2.3.10 (-)-endo-fenchol synthase 4.2.3.11 Sabinene-hydrate synthase 4.2.3.12 6-pyruvoyltetrahydropterin synthase 4.2.3.13 (+)-delta-cadinene synthase 4.2.3.14 Transferred entry: 4.2.3.119 and 4.2.3.120 4.2.3.15 Myrcene synthase 4.2.3.16 (4S)-limonene synthase 4.2.3.17 Taxadiene synthase 4.2.3.18 Abieta-7,13-diene synthase 4.2.3.19 Ent-kaurene synthase 4.2.3.20 (R)-limonene synthase 4.2.3.21 Vetispiradiene synthase 4.2.3.22 Germacradienol synthase 4.2.3.23 Germacrene-A synthase 4.2.3.24 Amorpha-4,11-diene synthase 4.2.3.25 S-linalool synthase 4.2.3.26 R-linalool synthase 4.2.3.27 Isoprene synthase 4.2.3.28 Ent-cassa-12,15-diene synthase 4.2.3.29 Ent-sandaracopimaradiene synthase 4.2.3.30 Ent-pimara-8(14),15-diene synthase 4.2.3.31 Ent-pimara-9(11),15-diene synthase 4.2.3.32 Levopimaradiene synthase 4.2.3.33 Stemar-13-ene synthase 4.2.3.34 Stemod-13(17)-ene synthase 4.2.3.35 Syn-pimara-7,15-diene synthase 4.2.3.36 Terpentetriene synthase 4.2.3.37 Epi-isozizaene synthase 4.2.3.38 Alpha-bisabolene synthase 4.2.3.39 Epi-cedrol synthase 4.2.3.40 (Z)-gamma-bisabolene synthase 4.2.3.41 Elisabethatriene synthase 4.2.3.42 Aphidicolan-16-beta-ol synthase 4.2.3.43 Fusicocca-2,10(14)-diene synthase 4.2.3.44 Isopimara-7,15-diene synthase 4.2.3.45 Phyllocladan-16-alpha-ol synthase 4.2.3.46 Alpha-farnesene synthase 4.2.3.47 Beta-farnesene synthase 4.2.3.48 (3S,6E)-nerolidol synthase 4.2.3.49 (3R,6E)-nerolidol synthase 4.2.3.50 (+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) 4.2.3.51 Beta-phellandrene synthase (neryl-diphosphate-cyclizing) 4.2.3.52 (4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) 4.2.3.53 (+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) 4.2.3.54 (-)-endo-alpha-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) 4.2.3.55 (S)-beta-bisabolene synthase 4.2.3.56 Gamma-humulene synthase 4.2.3.57 (-)-beta-caryophyllene synthase 4.2.3.58 Longifolene synthase 4.2.3.59 (E)-gamma-bisabolene synthase 4.2.3.60 Germacrene C synthase 4.2.3.61 5-epiaristolochene synthase 4.2.3.62 (-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing) 4.2.3.63 (+)-cubenene synthase 4.2.3.64 (+)-epicubenol synthase 4.2.3.65 Zingiberene synthase 4.2.3.66 Beta-selinene cyclase 4.2.3.67 Cis-muuroladiene synthase 4.2.3.68 Beta-eudesmol synthase 4.2.3.69 (+)-alpha-barbatene synthase 4.2.3.70 Patchoulol synthase 4.2.3.71 (E,E)-germacrene B synthase 4.2.3.72 Alpha-gurjunene synthase 4.2.3.73 Valencene synthase 4.2.3.74 Presilphiperfolanol synthase 4.2.3.75 (-)-germacrene D synthase 4.2.3.76 (+)-delta-selinene synthase 4.2.3.77 (+)-germacrene D synthase 4.2.3.78 Beta-chamigrene synthase 4.2.3.79 Thujopsene synthase 4.2.3.80 Alpha-longipinene synthase 4.2.3.81 Exo-alpha-bergamotene synthase 4.2.3.82 Alpha-santalene synthase 4.2.3.83 Beta-santalene synthase 4.2.3.84 10-epi-gamma-eudesmol synthase 4.2.3.85 Alpha-eudesmol synthase 4.2.3.86 7-epi-alpha-selinene synthase 4.2.3.87 Alpha-guaiene synthase 4.2.3.88 Viridiflorene synthase 4.2.3.89 (+)-beta-caryophyllene synthase 4.2.3.90 5-epi-alpha-selinene synthase 4.2.3.91 Cubebol synthase 4.2.3.92 (+)-gamma-cadinene synthase 4.2.3.93 Delta-guaiene synthase 4.2.3.94 Gamma-curcumene synthase 4.2.3.95 (-)-alpha-cuprenene synthase 4.2.3.96 Avermitilol synthase 4.2.3.97 (-)-delta-cadinene synthase 4.2.3.98 (+)-T-muurolol synthase 4.2.3.99 Labdatriene synthase 4.2.3.100 Bicyclogermacrene synthase 4.2.3.101 7-epi-sesquithujene synthase 4.2.3.102 Sesquithujene synthase 4.2.3.103 Ent-isokaurene synthase 4.2.3.104 Alpha-humulene synthase 4.2.3.105 Tricyclene synthase 4.2.3.106 (E)-beta-ocimene synthase 4.2.3.107 (+)-car-3-ene synthase 4.2.3.108 1,8-cineole synthase 4.2.3.109 (-)-sabinene synthase 4.2.3.110 (+)-sabinene synthase 4.2.3.111 (-)-alpha-terpineol synthase 4.2.3.112 (+)-alpha-terpineol synthase 4.2.3.113 Terpinolene synthase 4.2.3.114 Gamma-terpinene synthase 4.2.3.115 Alpha-terpinene synthase 4.2.3.116 (+)-camphene synthase 4.2.3.117 (-)-camphene synthase 4.2.3.118 2-methylisoborneol synthase 4.2.3.119 (-)-alpha-pinene synthase 4.2.3.120 (-)-beta-pinene synthase 4.2.3.121 (+)-alpha-pinene synthase 4.2.3.122 (+)-beta-pinene synthase 4.2.3.123 Beta-sesquiphellandrene synthase 4.2.3.124 2-deoxy-scyllo-inosose synthase 4.2.3.125 Alpha-muurolene synthase 4.2.3.126 Gamma-muurolene synthase 4.2.3.127 Beta-copaene synthase 4.2.3.128 Beta-cubebene synthase 4.2.3.129 (+)-sativene synthase 4.2.3.130 Tetraprenyl-beta-curcumene synthase 4.2.3.131 Miltiradiene synthase 4.2.3.132 Neoabietadiene synthase 4.2.3.133 Alpha-copaene synthase 4.2.3.134 5-phosphonooxy-L-lysine phospho-lyase 4.2.3.135 Delta(6)-protoilludene synthase 4.2.3.136 Alpha-isocomene synthase 4.2.3.137 (E)-2-epi-beta-caryophyllene synthase 4.2.3.138 (+)-epi-alpha-bisabolol synthase 4.2.3.139 Valerena-4,7(11)-diene synthase 4.2.3.140 Cis-abienol synthase 4.2.3.141 Sclareol synthase 4.2.3.142 7-epizingiberene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) 4.2.3.143 Kunzeaol synthase 4.2.3.144 Geranyllinalool synthase 4.2.3.145 Ophiobolin F synthase 4.2.3.146 Cyclooctat-9-en-7-ol synthase 4.2.3.147 Pimaradiene synthase 4.2.3.148 Cembrene C synthase 4.2.3.149 Nephthenol synthase 4.2.3.150 Cembrene A synthase 4.2.3.151 Pentamethylcyclopentadecatrienol synthase 4.2.3.152 2-epi-5-epi-valiolone synthase 4.2.3.153 (5-formylfuran-3-yl)methyl phosphate synthase 4.2.3.154 Demethyl-4-deoxygadusol synthase 4.2.3.155 2-epi-valiolone synthase 4.2.3.156 Hydroxysqualene synthase 4.2.3.157 (+)-isoafricanol synthase 4.2.3.158 (-)-spiroviolene synthase 4.2.3.159 Tsukubadiene synthase 4.2.3.160 (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase 4.2.3.161 (3S)-(+)-asterisca-2(9),6-diene synthase 4.2.3.162 (-)-alpha-amorphene synthase 4.2.3.163 (+)-corvol ether B synthase 4.2.3.164 (+)-eremophilene synthase 4.2.3.165 (1R,4R,5S)-(-)-guaia-6,10(14)-diene synthase 4.2.3.166 (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol synthase 4.2.3.167 Dolabella-3,7-dien-18-ol synthase 4.2.3.168 Dolathalia-3,7,11-triene synthase 4.2.3.169 7-epi-alpha-eudesmol synthase 4.2.3.170 4-epi-cubebol synthase 4.2.3.171 (+)-corvol ether A synthase 4.2.3.172 10-epi-juneol synthase 4.2.3.173 Tau-cadinol synthase 4.2.3.174 (2E,6E)-hedycaryol synthase 4.2.3.175 10-epi-cubebol synthase 4.2.3.176 Sesterfisherol synthase 4.2.3.177 Beta-thujene synthase 4.2.3.178 Stellata-2,6,19-triene synthase 4.2.3.179 Guaia-4,6-diene synthase 4.2.3.180 Pseudolaratriene synthase 4.2.3.181 Selina-4(15),7(11)-diene synthase 4.2.3.182 Pristinol synthase 4.2.3.183 Nezukol synthase 4.2.3.184 5-hydroxy-alpha-gurjunene synthase 4.2.3.185 Ent-atiserene synthase 4.2.3.186 Ent-13-epi-manoyl oxide synthase 4.2.3.187 (2Z,6E)-hedycaryol synthase 4.2.3.188 Beta-geranylfarnesene synthase 4.2.3.189 9,13-epoxylabda-14-ene synthase 4.2.3.190 Manoyl oxide synthase 4.2.3.191 Cycloaraneosene synthase 4.2.3.192 Labda-7,13(16),14-triene synthase 4.2.3.193 (12E)-labda-8(17),12,14-triene synthase 4.2.3.194 (-)-drimenol synthase 4.2.3.195 Rhizathalene A synthase 4.2.3.n1 Transferred entry: 4.2.3.38 4.2.3.n2 Delta-selinene synthase 4.2.3.n3 Transferred entry: 4.2.3.56 4.2.3.n4 Transferred entry: 4.2.3.117 4.2.3.n5 Transferred entry: 4.2.3.52 4.2.3.n6 Transferred entry: 4.2.3.113 4.2.3.n7 Transferred entry: 4.2.3.119 4.2.3.n8 Transferred entry: 4.2.3.103 4.2.3.n9 Transferred entry: 4.2.3.44 4.2.3.n10 Transferred entry: 4.2.3.62 4.2.3.n11 Selinene synthase 4.2.3.n12 Transferred entry: 4.2.3.65 4.2.3.n13 Transferred entry: 4.2.3.75 4.2.3.n14 Transferred entry: 4.2.3.118 4.2.99.1 Transferred entry: 4.2.2.1 4.2.99.2 Transferred entry: 4.2.3.1 4.2.99.3 Transferred entry: 4.2.2.2 4.2.99.4 Transferred entry: 4.2.2.3 4.2.99.5 Deleted entry 4.2.99.6 Transferred entry: 4.2.2.5, 4.2.2.20 and 4.2.2.21 4.2.99.7 Transferred entry: 4.2.3.2 4.2.99.8 Transferred entry: 2.5.1.47 4.2.99.9 Transferred entry: 2.5.1.48 4.2.99.10 Transferred entry: 2.5.1.49 4.2.99.11 Transferred entry: 4.2.3.3 4.2.99.12 Carboxymethyloxysuccinate lyase 4.2.99.13 Transferred entry: 2.5.1.50 4.2.99.14 Transferred entry: 2.5.1.51 4.2.99.15 Transferred entry: 2.5.1.52 4.2.99.16 Transferred entry: 2.5.1.53 4.2.99.17 Transferred entry: 2.5.1.51 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase 4.2.99.19 Transferred entry: 4.4.1.23 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 4.2.99.21 Isochorismate lyase 4.2.99.22 Tuliposide A-converting enzyme 4.2.99.23 Tuliposide B-converting enzyme 4.2.99.n1 Transferred entry: 4.2.99.20 4.3.1.1 Aspartate ammonia-lyase 4.3.1.2 Methylaspartate ammonia-lyase 4.3.1.3 Histidine ammonia-lyase 4.3.1.4 Formimidoyltetrahydrofolate cyclodeaminase 4.3.1.5 Transferred entry: 4.3.1.23, 4.3.1.24 and 4.3.1.25 4.3.1.6 Beta-alanyl-CoA ammonia-lyase 4.3.1.7 Ethanolamine ammonia-lyase 4.3.1.8 Transferred entry: 2.5.1.61 4.3.1.9 Glucosaminate ammonia-lyase 4.3.1.10 Serine-sulfate ammonia-lyase 4.3.1.11 Deleted entry 4.3.1.12 Ornithine cyclodeaminase 4.3.1.13 Carbamoyl-serine ammonia-lyase 4.3.1.14 3-aminobutyryl-CoA ammonia-lyase 4.3.1.15 Diaminopropionate ammonia-lyase 4.3.1.16 Threo-3-hydroxy-L-aspartate ammonia-lyase 4.3.1.17 L-serine ammonia-lyase 4.3.1.18 D-serine ammonia-lyase 4.3.1.19 Threonine ammonia-lyase 4.3.1.20 Erythro-3-hydroxy-L-aspartate ammonia-lyase 4.3.1.21 Transferred entry: 4.3.1.9 4.3.1.22 3,4-dihydroxyphenylalanine reductive deaminase 4.3.1.23 Tyrosine ammonia-lyase 4.3.1.24 Phenylalanine ammonia-lyase 4.3.1.25 Phenylalanine/tyrosine ammonia-lyase 4.3.1.26 Transferred entry: 1.21.98.2 4.3.1.27 Threo-3-hydroxy-D-aspartate ammonia-lyase 4.3.1.28 L-lysine cyclodeaminase 4.3.1.29 D-glucosaminate-6-phosphate ammonia lyase 4.3.1.30 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase 4.3.1.31 L-tryptophan ammonia lyase 4.3.1.32 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase 4.3.2.1 Argininosuccinate lyase 4.3.2.2 Adenylosuccinate lyase 4.3.2.3 Ureidoglycolate lyase 4.3.2.4 Purine imidazole-ring cyclase 4.3.2.5 Peptidylamidoglycolate lyase 4.3.2.6 Gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase 4.3.2.7 Glutathione-specific gamma-glutamylcyclotransferase 4.3.2.8 Gamma-glutamylamine cyclotransferase 4.3.2.9 Gamma-glutamylcyclotransferase 4.3.2.10 Imidazole glycerol-phosphate synthase 4.3.3.1 3-ketovalidoxylamine C-N-lyase 4.3.3.2 Strictosidine synthase 4.3.3.3 Deacetylisoipecoside synthase 4.3.3.4 Deacetylipecoside synthase 4.3.3.5 4'-demethylrebeccamycin synthase 4.3.3.6 Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) 4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase 4.3.3.n1 Transferred entry: 4.1.99.20 4.3.99.1 Transferred entry: 4.2.1.104 4.3.99.2 Transferred entry: 7.2.4.1 4.3.99.3 7-carboxy-7-deazaguanine synthase 4.3.99.4 Choline trimethylamine-lyase 4.4.1.1 Cystathionine gamma-lyase 4.4.1.2 Homocysteine desulfhydrase 4.4.1.3 Dimethylpropiothetin dethiomethylase 4.4.1.4 Alliin lyase 4.4.1.5 Lactoylglutathione lyase 4.4.1.6 S-alkylcysteine lyase 4.4.1.7 Transferred entry: 2.5.1.18 4.4.1.8 Cystathionine beta-lyase 4.4.1.9 L-3-cyanoalanine synthase 4.4.1.10 Cysteine lyase 4.4.1.11 Methionine gamma-lyase 4.4.1.12 Deleted entry 4.4.1.13 Cysteine-S-conjugate beta-lyase 4.4.1.14 1-aminocyclopropane-1-carboxylate synthase 4.4.1.15 D-cysteine desulfhydrase 4.4.1.16 Selenocysteine lyase 4.4.1.17 Holocytochrome-c synthase 4.4.1.18 Transferred entry: 1.8.3.5 4.4.1.19 Phosphosulfolactate synthase 4.4.1.20 Leukotriene-C(4) synthase 4.4.1.21 S-ribosylhomocysteine lyase 4.4.1.22 S-(hydroxymethyl)glutathione synthase 4.4.1.23 2-hydroxypropyl-CoM lyase 4.4.1.24 (2R)-sulfolactate sulfo-lyase 4.4.1.25 L-cysteate sulfo-lyase 4.4.1.26 Olivetolic acid cyclase 4.4.1.27 Transferred entry: 3.13.1.5 4.4.1.28 L-cysteine desulfidase 4.4.1.29 Phycobiliprotein cysteine-84 phycobilin lyase 4.4.1.30 Phycobiliprotein beta-cysteine-155 phycobilin lyase 4.4.1.31 Phycoerythrocyanin alpha-cysteine-84 phycoviolobilin lyase/isomerase 4.4.1.32 C-phycocyanin alpha-cysteine-84 phycocyanobilin lyase 4.4.1.33 R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase 4.4.1.34 Isoprene-epoxide--glutathione S-transferase 4.4.1.35 L-cystine beta-lyase 4.4.1.36 Hercynylcysteine S-oxide lyase 4.4.1.37 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase 4.5.1.1 DDT-dehydrochlorinase 4.5.1.2 3-chloro-D-alanine dehydrochlorinase 4.5.1.3 Dichloromethane dehalogenase 4.5.1.4 L-2-amino-4-chloropent-4-enoate dehydrochlorinase 4.5.1.5 S-carboxymethylcysteine synthase 4.6.1.1 Adenylate cyclase 4.6.1.2 Guanylate cyclase 4.6.1.3 Transferred entry: 4.2.3.4 4.6.1.4 Transferred entry: 4.2.3.5 4.6.1.5 Transferred entry: 4.2.3.7 4.6.1.6 Cytidylate cyclase 4.6.1.7 Transferred entry: 4.2.3.8 4.6.1.8 Transferred entry: 4.2.3.10 4.6.1.9 Transferred entry: 4.2.3.11 4.6.1.10 Transferred entry: 4.2.3.12 4.6.1.11 Transferred entry: 4.2.3.13 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.13 Phosphatidylinositol diacylglycerol-lyase 4.6.1.14 Glycosylphosphatidylinositol diacylglycerol-lyase 4.6.1.15 FAD-AMP lyase (cyclizing) 4.6.1.16 tRNA-intron lyase 4.6.1.17 Cyclic pyranopterin monophosphate synthase 4.7.1.1 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase 4.99.1.1 Protoporphyrin ferrochelatase 4.99.1.2 Alkylmercury lyase 4.99.1.3 Sirohydrochlorin cobaltochelatase 4.99.1.4 Sirohydrochlorin ferrochelatase 4.99.1.5 Aliphatic aldoxime dehydratase 4.99.1.6 Indoleacetaldoxime dehydratase 4.99.1.7 Phenylacetaldoxime dehydratase 4.99.1.8 Heme ligase 4.99.1.9 Coproporphyrin ferrochelatase 4.99.1.10 Magnesium dechelatase 4.99.1.11 Sirohydrochlorin nickelchelatase 4.99.1.12 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase