A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_09. Read more about EC 7 here.

ENZYME entry: EC 4.2.3.107

Accepted Name
(+)-car-3-ene synthase.
Alternative Name(s)
3-carene cyclase.
Reaction catalysed
Geranyl diphosphate <=> (+)-car-3-ene + diphosphate
Comment(s)
  • The enzyme reacts with (3S)-linalyl diphosphate twice as rapidly as geranyl diphosphate, but 25 times as rapidly as (3R)-linalyl diphosphate.
  • It is assumed that (3S)-linalyl diphosphate is normally formed as an enzyme bound intermediate in the reaction.
  • In the reaction the 5-pro-R hydrogen of geranyl diphosphate is eliminated during cyclopropane ring formation.
  • In Picea abies (Norway spruce) and Picea sitchensis (Sitka spruce) terpinolene is also formed.
  • See EC 4.2.3.113.
  • (+)-car-3-ene is associated with resistance of Picea sitchensis (Sitka spruce) to white pine weevil.
Cross-references
BRENDA4.2.3.107
EC2PDB4.2.3.107
ExplorEnz4.2.3.107
PRIAM enzyme-specific profiles4.2.3.107
KEGG Ligand Database for Enzyme Nomenclature4.2.3.107
IUBMB Enzyme Nomenclature4.2.3.107
IntEnz4.2.3.107
MEDLINEFind literature relating to 4.2.3.107
MetaCyc4.2.3.107
UniProtKB/Swiss-Prot
Q84SM8, 3CAR1_PICAB;  C7ASI9, 3CAR1_PICGL;  F1CKI6, 3CAR1_PICSI;  
F1CKI8, 3CAR2_PICSI;  F1CKI9, 3CAR3_PICSI;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-