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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 22.214.171.124
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|(+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate
|(2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene|
- The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-
- Following dephosphorylation of (2Z,6Z)-farnesyl diphosphate,
the (2Z,6Z)-farnesyl carbocation is converted to either the (6R)- or
the (6S)-bisabolyl cations depending on the stereochemistry of the
- The (6R)-bisabolyl cation will then lead to the formation of (+)-
alpha-santalene (see EC 126.96.36.199), while the (6S)-bisabolyl cation
will give rise to (-)-endo-alpha-bergamotene (see EC 188.8.131.52),
as well as (+)-endo-beta-bergamotene.
- Small amounts of (-)-epi-beta-santalene are also formed from the
(6R)-bisabolyl cation and small amounts of (-)-exo-alpha-bergamotene
are formed from the (6S)-bisabolyl cation.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-