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ENZYME entry: EC 4.2.3.56

Accepted Name
Gamma-humulene synthase.
Reaction catalysed
Farnesyl-diphosphate <=> gamma-humulene + diphosphate
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • Has a broad product range.
  • While gamma-humulene is the major product, sibirene, longifolene, beta-himachalene, gamma-himachalene and alpha-himachalene are produced in appreciable amounts and further 47 other minor products can also be detected.
  • The enzyme can use geranyl diphosphate as a substrate, producing mainly limonene and terpinolene as the major products.
  • Formerly EC 4.2.3.n3.
Cross-references
BRENDA4.2.3.56
EC2PDB4.2.3.56
ExplorEnz4.2.3.56
PRIAM enzyme-specific profiles4.2.3.56
KEGG Ligand Database for Enzyme Nomenclature4.2.3.56
IUBMB Enzyme Nomenclature4.2.3.56
IntEnz4.2.3.56
MEDLINEFind literature relating to 4.2.3.56
MetaCyc4.2.3.56
UniProtKB/Swiss-Prot
O64405, TPSD5_ABIGR

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