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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.2.3.75

Accepted Name
(-)-germacrene D synthase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> (-)-germacrene D + diphosphate
Comment(s)
  • In Solidago canadensis the biosynthesis results in the pro-R hydrogen at C-1 of the farnesy diphosphate ending up at C-11 of the (-)- germacrene D.
  • With Streptomyces coelicolor the pro-S hydrogen at C-1 ends up at C-11 of the (-)-germacrene D.
  • Formerly EC 4.2.3.n13.
Cross-references
BRENDA4.2.3.75
EC2PDB4.2.3.75
ExplorEnz4.2.3.75
PRIAM enzyme-specific profiles4.2.3.75
KEGG Ligand Database for Enzyme Nomenclature4.2.3.75
IUBMB Enzyme Nomenclature4.2.3.75
IntEnz4.2.3.75
MEDLINEFind literature relating to 4.2.3.75
MetaCyc4.2.3.75
UniProtKB/Swiss-Prot
Q9X839, CYC2_STRCO;  Q5SBP6, GDS_OCIBA;  Q49SP4, TPGD1_POGCB;  
Q49SP6, TPGD2_POGCB;  J9RLZ7, TPS1_VALOF;  I6QPS5, TPS5_MATCR;  
Q6Q3H3, TPSGD_VITVI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-