A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 4.2.3.96
| Accepted Name |
|---|
| Avermitilol synthase.
|
| Reaction catalysed |
|---|
| (2E,6E)-farnesyl diphosphate + H(2)O <=> avermitilol + diphosphate |
| Cofactor(s) |
|---|
| Mg(2+).
|
| Comment(s) |
|---|
- The recombinent enzyme gives avermitilol (85%) plus traces of
germacrene A, germacrene B and viridiflorol.
- The (1S)-hydrogen of farnesyl diphosphate is retained.
|
| Cross-references |
|---|
| BRENDA | 4.2.3.96 |
| EC2PDB | 4.2.3.96 |
| ExplorEnz | 4.2.3.96 |
| PRIAM enzyme-specific profiles | 4.2.3.96 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.2.3.96 |
| IUBMB Enzyme Nomenclature | 4.2.3.96 |
| IntEnz | 4.2.3.96 |
| MEDLINE | Find literature relating to 4.2.3.96 |
| MetaCyc | 4.2.3.96 |
| UniProtKB/Swiss-Prot |
|
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