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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
4'-demethylrebeccamycin synthase.
Alternative Name(s)
Arcyriaflavin A N-glycosyltransferase.
Reaction catalysed
4'-O-demethylrebeccamycin + H(2)O <=> dichloro-arcyriaflavin A + beta-D-glucose
  • This enzyme catalyzes a step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes.
  • The enzyme is a glycosylase, and acts in the reverse direction to that shown.
  • It has a wide substrate range, and was shown to glycosylate several substrates, including the staurosporine aglycone, EJG-III-108A, J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole.
PRIAM enzyme-specific profiles4.3.3.5
KEGG Ligand Database for Enzyme Nomenclature4.3.3.5
IUBMB Enzyme Nomenclature4.3.3.5
MEDLINEFind literature relating to

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-