ENZYME entry: EC 4.3.3.5
Accepted Name |
4'-demethylrebeccamycin synthase.
|
Alternative Name(s) |
Arcyriaflavin A N-glycosyltransferase. |
Reaction catalysed |
4'-O-demethylrebeccamycin + H(2)O <=> dichloro-arcyriaflavin A + beta-D-glucose |
Comment(s) |
- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
an indolocarbazole alkaloid produced by the bacterium Lechevalieria
aerocolonigenes.
- The enzyme is a glycosylase, and acts in the reverse direction to
that shown.
- It has a wide substrate range, and was shown to glycosylate several
substrates, including the staurosporine aglycone, EJG-III-108A,
J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole.
|
Cross-references |
BRENDA | 4.3.3.5 |
EC2PDB | 4.3.3.5 |
ExplorEnz | 4.3.3.5 |
PRIAM enzyme-specific profiles | 4.3.3.5 |
KEGG Ligand Database for Enzyme Nomenclature | 4.3.3.5 |
IUBMB Enzyme Nomenclature | 4.3.3.5 |
IntEnz | 4.3.3.5 |
MEDLINE | Find literature relating to 4.3.3.5 |
MetaCyc | 4.3.3.5 |
UniProtKB/Swiss-Prot |
|
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