ENZYME entry: EC 4.6.1.16

Accepted Name

tRNA-intron lyase

Alternative Name(s)

tRNA splicing endonuclease

Reaction catalysed

pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus

Comment(s)

The enzyme catalyzes the final stage in the maturation of tRNA molecules.
Formerly EC 3.1.27.9.

Cross-references

BRENDA

4.6.1.16

EC2PDB

4.6.1.16

ExplorEnz

4.6.1.16

PRIAM enzyme-specific profiles

4.6.1.16

KEGG Ligand Database for Enzyme Nomenclature

4.6.1.16

IUBMB Enzyme Nomenclature

4.6.1.16

IntEnz

4.6.1.16

MEDLINE

Find literature relating to 4.6.1.16

MetaCyc

4.6.1.16

Rhea expert-curated reactions

4.6.1.16

UniProtKB/Swiss-Prot

Q9YBF1, ENDA_AERPE	O29362, ENDA_ARCFU	Q5UYF6, ENDA_HALMA
B0R7C0, ENDA_HALS3	Q9HN82, ENDA_HALSA	O07118, ENDA_HALVD
A2BIW2, ENDA_HYPBU	Q8TGX1, ENDA_METAC	Q46FK9, ENDA_METBF
Q12X51, ENDA_METBU	Q58819, ENDA_METJA	Q8TGZ7, ENDA_METKA
Q8PZI1, ENDA_METMA	Q6LY59, ENDA_METMP	O07165, ENDA_METTH
A6UPD9, ENDA_METVS	Q74MP4, ENDA_NANEQ	Q3IU70, ENDA_NATPD
Q6L1P9, ENDA_PICTO	Q9UY33, ENDA_PYRAB	Q8ZVI1, ENDA_PYRAE
A4WLV3, ENDA_PYRAR	Q8U429, ENDA_PYRFU	O58033, ENDA_PYRHO
A1RSY7, ENDA_PYRIL	B1Y9D1, ENDA_PYRNV	Q97ZY3, ENDA_SACS2
Q4JAF4, ENDA_SULAC	C3N6N2, ENDA_SULIA	C4KIA4, ENDA_SULIK
C3MQX7, ENDA_SULIL	C3MWW5, ENDA_SULIM	C3NGJ0, ENDA_SULIN
C3N746, ENDA_SULIY	Q975R3, ENDA_SULTO	Q9HIY5, ENDA_THEAC
C5A2D9, ENDA_THEGJ	Q5JHP5, ENDA_THEKO	B6YXU4, ENDA_THEON
Q97BQ3, ENDA_THEVO	Q9M1E8, SEN21_ARATH	Q9LSS3, SEN22_ARATH
Q5ZIN2, SEN2_CHICK	Q74ZY5, SEN2_EREGS	Q8NCE0, SEN2_HUMAN
Q6P7W5, SEN2_MOUSE	Q9P6Y2, SEN2_NEUCR	Q5Z6B1, SEN2_ORYSJ
Q5M954, SEN2_RAT	Q8TFH7, SEN2_SCHPO	P16658, SEN2_YEAST
Q754T3, SEN34_EREGS	Q9BSV6, SEN34_HUMAN	Q8BMZ5, SEN34_MOUSE
Q7SAK9, SEN34_NEUCR	O60156, SEN34_SCHPO	P39707, SEN34_YEAST

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