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ENZYME entry: EC 4.6.1.22

Accepted Name
Bacillus subtilis ribonuclease.
Alternative Name(s)
(RNA) 5'-hydroxy-ribonucleotide-3'-(RNA fragment)-lyase (cyclicizing; (RNA fragment)-3'- nucleoside -2',3'-cyclophosphate-forming).
Bacterial RNA lyase.
Reaction catalysed
RNA <=> a 5'-hydroxy-ribonucleotide + n nucleoside-2',3'-cyclophosphates
Comment(s)
  • This enzyme catalyzes endonucleolytic cleavage to 2',3'-cyclic nucleotides.
  • The cyclic products may be hydrolyzed to the corresponding 3'-phosphates by EC 3.1.4.16.
  • The enzyme from Bacillus subtilis is inhibited by ATP.
  • Formerly EC 3.1.27.2.
Cross-references
BRENDA4.6.1.22
EC2PDB4.6.1.22
ExplorEnz4.6.1.22
PRIAM enzyme-specific profiles4.6.1.22
KEGG Ligand Database for Enzyme Nomenclature4.6.1.22
IUBMB Enzyme Nomenclature4.6.1.22
IntEnz4.6.1.22
MEDLINEFind literature relating to 4.6.1.22
MetaCyc4.6.1.22
UniProtKB/Swiss-Prot
U2UMQ6, CS12A_ACISB;  A0Q7Q2, CS12A_FRATN;  

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